Results 91 to 100 of about 311,135 (313)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The macrobrachium culture industry in Thailand. [PDF]
, 2004 Giant freshwater prawn (Macrobrachum rosenbergii) is one of the most important economic species in Thailand as well as in many Southeast Asian countries.
Sodsuk, Panom, Uraiwa, Supattra
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Analysing Linkages between Strategy, Performance, Management Structure and Culture in the Spanish Fresh Produce Industry [PDF]
This article reports the results of an industry-level study that seeks to identify empirical regularities between firm strategy, management style, organisational structure and performance in the Spanish fresh fruit and vegetable (fresh produce) industry ...
Poole, Nigel D., Martinez, Marian Garcia
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Culture: Development, industry, distribution [PDF]
, 2002 Culture: development, industry ...
O'Regan, Tom +6 more
core +1 more source
Tabus sexuais entre professores e alunos Sexual taboos among teachers and students
Pro-Posições, 2008 O poder da sexualidade nas relações entre professores e alunos é tão intenso quanto o esforço feito pelos agentes educacionais em negá-lo. O termo tabu representa a exata designação do que tal terminologia suscita: algo misterioso e, principalmente ...
Antônio Zuin
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Culture and the Survival of UK Independent Games Software Firms [PDF]
This paper reports on qualitative research that investigates the culture of survival among entrepreneurial UK games software development firms within the interactive entertainment industry.
Denise Tsang
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Relationship marketing with customers in the hotel industry in Thailand [PDF]
, 2009 This thesis explores the scope, nature and form of relationship marketing in the hotel industry in Thailand. For the last twenty years, relationship marketing has attracted enormous interest from both academic researchers and business practitioners ...
Preechanont, P, Preechanont, Piyanuch
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