Results 81 to 90 of about 6,653,826 (260)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
A model for customer-focused culture change in the speculative house-building industry : executive summary [PDF]
The UK house-building industry is increasingly criticised for the quality of its products. Its business drivers are less focused on the needs of customers compared with much of the manufacturing sector.
Craig, David
core
Rethinking Culture and Cultural Analysis
, 2013 The texts in this collection are revised versions of presentations given at the Coimbra International Conference on the Semantics of Culture emph Why ``Culture''?, held on November 24-25, 2011.
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
AEC industry culture: a need for change [PDF]
, 2004 Future development in determining new and improved ways for Architectural, Engineering, and Contractor (AEC) industry participants to do business through information and communication technology (ICT) tools and systems is dependent on the innovation of ...
Weippert, Achim, Kajewski, Stephen L.
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Sport and sport media as a culture industry product
Spor Bilimleri Araştırmaları Dergisi, 2018 Today, the concept ofsports is associated with commercialized and industrialized elite sportsinstead of the activities that are required to sustain healthy lives. Sport isthe first area in which capitalism can deepen its hold on society and renew it.This
Selami Özsoy
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
, 1970 23 pages; available for download at the link below.In order to promote an orderly growth of ocean-related industry [in Texas] and, at the same time, insure proper management of the natural environment, it appears necessary that within the framework of ...
Industry Advisory Group
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