Results 81 to 90 of about 311,135 (313)

Axiology in the domain of heritage: The concept of „Values” and Culture Industry [PDF]

open access: yes, 2014
The concept of “values” related to heritage in a broad sense and the other different elements actively contributing to the overall appreciation and fruitful exploitation of our legacy.
RONCHI, ALFREDO
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Conceptualizing the roles of psychological safety, caring management and inclusiveness in safety culture maturity in Malaysia’s oil and gas industry [PDF]

open access: yes
The number of recent studies related to safety culture maturity in the context of oil and gas industry in Malaysia is rather limited, considering the fact that the oil and gas is a high-risk industry.
Mustaffa, Masfarita   +2 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The Philippine aquaculture industry [PDF]

open access: yes, 1988
The aquaculture sector of the Philippine fishing industry registered the highest growth rate of 12.5% in 1977-1986. The contribution of aquaculture to the total fish production was equivalent to 24% in 1986 compared to only 85 in the early 1970's.
Camacho, Arsenio S.   +1 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A model for customer-focused culture change in the speculative house-building industry : executive summary [PDF]

open access: yes
The UK house-building industry is increasingly criticised for the quality of its products. Its business drivers are less focused on the needs of customers compared with much of the manufacturing sector.
Craig, David
core  

An investigation into the impact of culture on construction project performance [PDF]

open access: yes, 2007
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of Philosophy (PhD)For many years, government backed reports have continued to deplore the poor performance of the construction ...
Ankrah, Nii Amponsah, Ankrah, Nii
core  

O livro didático como mercadoria The textbook as commodity

open access: yesPro-Posições, 2012
Para Marx, a mercadoria é a principal categoria para o entendimento do capitalismo. Mediadora das relações sociais, ela é, antes, uma coisa que serve para realizar as necessidades do ser humano.
Kazumi Munakata
doaj   +1 more source

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