Results 61 to 70 of about 1,813,775 (308)

Libre culture: meditations on free culture [PDF]

open access: yes, 2008
Libre Culture is the essential expression of the free culture/copyleft movement. This anthology, brought together here for the first time, represents the early groundwork of Libre Society thought.
Berry, David M, Moss, Giles
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Outshining Aura: How Modernist Film Refashions the Myth of Don Quixote

open access: yesOpen Cultural Studies, 2017
This paper aims at examining the first Don Quixote sound film The Adventures of Don Quixote, directed by G.W. Pabst in 1933, as well as the songs and musical themes that two great French composers, Ravel and Ibert composed for the Russian baritone Feodor
Sánchez-Pardo Esther
doaj   +1 more source

Pleasure, profit and pain: Alcohol in New Zealand and the contemporary culture of intoxication [PDF]

open access: yes, 2013
This book details the rich, complex and often contested role of alcohol in New Zealand society. It explores the three fundamental alcohol rights that continue to fight for dominance of the national drinking culture: the rights of individual drinkers to ...
Campbell, Maxine M.   +3 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Video game preservation in the UK: a survey of records management practices [PDF]

open access: yes, 2014
Video games are a cultural phenomenon; a medium like no other that has become one of the largest entertainment sectors in the world. While the UK boasts an enviable games development heritage, it risks losing a major part of its cultural output through ...
Bachell, Alasdair, Barr, Matthew
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Aquaculture Asia, Vol. 11, No. 2, pp.1-38. April-June 2006 [PDF]

open access: yes, 2006
Selection of high-health postlarvae: a prerequisite for sustainability of the Indian shrimp industry, by S. Saurabh, V. Kumar, S. Karanth and G. Venkateshwarlu. Nucleotides: novel immunostimulants in aquaculture feed, by P. Kalaimani Arasi, N. Felix.

core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Jenseits von Binarität

open access: yesCahiers d’Études Germaniques
This article shows the extent to which the work Faust (2017) by German visual artist Anne Imhof utilizes the aesthetic as well as the socio-critical potential of performance, understood as transgression.
Kathrin‑Julie ZENKER
doaj   +1 more source

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