Results 41 to 50 of about 6,653,826 (260)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Safety culture and the australian heavy vehicle industry : a concept in chaos : an industry in need [PDF]
, 2014 This research proposed a new framework for safety culture and examined the influence that culture has on safety in the heavy vehicle industry. The results gave evidence for an industry wide culture, allowing future safety interventions to be designed in ...
Edwards, Jason R.
core
Industry super and the Australian economy [PDF]
, 2016 This report highlights Australia’s not-for-profit industry super funds are effectively leveraging the scale and long-term investment horizon to invest in real economy assets which have been the foundation of superior member returns. This study attempts
Industry Super Australia
core +1 more source
Structural model of celebrityization and daily life of social network users (case study of Tehrani users of Instagram social network) [PDF]
مطالعات رسانههای نوینToday, the media world and its audiences are experiencing a paradigm shift from an era that was characterized by a one-sided, ideology-driven media industry that favored a one-sided, monologue, and dictatorial approach. In contrast, the digital world and
Azam Velayati +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
The Fine Art of Commercial Freedom: British Music Videos and Film Culture [PDF]
, 2014 An outline and analysis of the British music video industry and its impact on film culture in the 1990s and ...
Caston, Emily
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Project culture in the Chinese construction industry: perceptions of contractors [PDF]
, 2009 In recent years culture has become one of the most studied topicsin project management research. Some studies have investigatedthe infl uence of culture at different levels – such as nationalculture, industry culture, organisational culture and ...
Zillante, George +5 more
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