Results 121 to 130 of about 22,966,310 (260)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

The use of video games and issues of aggressive behavior among pre-adolescent students

open access: yesΨυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής Εταιρείας
The aim of this research is to investigate the relationship between the use of video games and aggressive behavior among students of the fifth and the sixth grade of primary school. The sample consisted of 225 students.
Μαρία Τζιβάνη   +1 more
doaj   +1 more source

On Strategies for International Communication of Jingdezhen Ceramic Culture in the All-media Era [PDF]

open access: yes
Cultural soft power is a core factor for measuring the comprehensive national strength of a country. Jingdezhen ceramic culture is an important part of Chinese culture, so its international communication is of great significance to enhance the soft power
DENG, Hongchun, MA, Yuehua
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

FASHION, MEDIA AND CULTURE: PERSPECTIVES ON GLOBAL LIFESTYLES

open access: yes
Description: The Fashion, Media, Culture series brings together contributions from different contexts, countries, and disciplinary fields in order to offer a renewed and updated approach to issues related to mass culture, media, communication, and ...
Federica Muzzarelli   +2 more
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Ethical perceptions and learning engagement in AI-assisted translation: a behavioral psychology study of English learners

open access: yesFrontiers in Psychology
The rapid integration of artificial intelligence (AI) into language learning environments is reshaping translation pedagogy while raising important ethical and behavioral considerations. This research examines the structural relationship between students’
Lingli Zhang, Qian Li
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

The funding of the BBC Government response to the third report from the Culture, Media and Sport Committee, Session 1999-2000

open access: yes, 2000
Presented to Parliament by the Secretary of State for Culture, Media and Sport March 2000Available from British Library Document Supply Centre-DSC:OP-CM/4674 / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Department for Culture, Media and Sport, London (United Kingdom)
core  

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