Results 111 to 120 of about 3,626,823 (307)

New Muslim Cool: Engaging Stakeholders in the Filmmaking Process [PDF]

open access: yes, 2010
Provides an overview of the production, funding model, project partners, and impact of New Muslim Cool, a documentary film on American Muslim youth culture with a mission to promote interfaith dialogue.
Nina Keim
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The Digital Switchover of Doordarshan: Intriguing Dynamics of Policy Options

open access: yesMedijske Studije, 2015
In a country with few channels occupying the terrestrial space – all of which are owned by the public broadcaster – what is the rationale behind the expensive and mandatory transition to digital terrestrial television?
Vibodh Parthasarathi, Supriya Chotani
doaj  

Media And Government Relations In Papua New Guinea [PDF]

open access: yes, 2006
All is not well with news media in Papua New Guinea. Media and government relations are stressed, a situation adverse to the country's development. Media organisations have to deal with operational difficulties, threats against editorial freedom, and ...
Duffield, Lee
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

The use of video games and issues of aggressive behavior among pre-adolescent students

open access: yesΨυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής Εταιρείας
The aim of this research is to investigate the relationship between the use of video games and aggressive behavior among students of the fifth and the sixth grade of primary school. The sample consisted of 225 students.
Μαρία Τζιβάνη   +1 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Media Culture 2020: collaborative teaching and blended learning using social media and cloud-based technologies [PDF]

open access: yes, 2015
The Media Culture 2020 project was considered to be a great success by all the partners, academics and especially the students who took part. It is a true example of an intercultural, multidisciplinary, blended learning experience in higher education ...
Field, James   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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