Results 91 to 100 of about 3,626,823 (307)

High aspect reactor vessel and method of use [PDF]

, 1992
An improved bio-reactor vessel and system useful for carrying out mammalian cell growth in suspension in a culture media are presented. The main goal of the invention is to grow and maintain cells under a homogeneous distribution under acceptable ...
Sams, Clarence F., Schwarz, Ray P., Wolf, David A.   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The Politics of Disconnective Media: Unraveling the Materiality of Discourses on Disconnectivity

Media and Communication
The commodification of disconnection has attracted growing scholarly attention. Previous research highlighted the instrumentalisation of disconnection for productivity, self-governance, and healthy life. Researchers have also explored the politics of the
Veysel Bozan, Emiliano Treré
doaj   +1 more source

An Undergraduate Collaborative Team Model to Engage Nursing Students in Research [PDF]

, 2017
Purpose: Student-faculty collaboration on research is an effective model to engage undergraduate students in the research process outside of the traditional curriculum. Using this model, a student-faculty team developed a longitudinal study about college
Kessler, Theresa A, Kurtz, Christine P
core   +4 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Ford Foundation Vietnam [PDF]

, 2008
Provides an overview of the foundation's programs and key strategies in Vietnam in development finance; education and scholarship; environment and development; international cooperation; media, arts and culture; and sexuality and reproductive ...

core  

Anti-Nirvana: crime, culture and instrumentalism in the age of insecurity [PDF]

, 2005
‘Anti-Nirvana’ explores the relationship between consumer culture, media and criminal motivations. It has appeared consistently on the list of the top-ten most-read articles in this award-winning international journal, and it mounts a serious neo ...
Baudrillard, J., Bauman, Z., Bauman, Z., Beck, U., Beck, U., Bourdieu, P., Bourdieu, P., Byrne, D., Castells, M., Chesney-Lind, M., Davis, M., Debord, G., Downes, D., Eagleton, T., Elias, N., Faludi, S., Fletcher, J., Freud, S., Freud, S., Gray, J., Habermas, J., Hall, S., Hall, Steve, Hobsbawm, E., Horne, R., Hutton, W., Jenks, C., Lasch, C., Lasch, C., Lea, J., MacInnes, J., Miller, W. B., Shover, N., Simon Winlow, Steve Hall, Sumner, C., Taylor, I., Westergaard, J. H., Willis, P., Wilson, W. J., Winlow, S., Winlow, S., Winlow, S., Young, J.   +43 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Mediated intimacy: Sex advice in media culture [PDF]

, 2018
The bold argument of Mediated Intimacy (Barker et al., 2018)1 is that media of various kinds play an increasingly important role in shaping people’s knowledge, desires, practices and expectations about intimate relationships.
Barker, M-J., Gill, R., Harvey, L.
core   +3 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source