Results 91 to 100 of about 21,799,908 (300)
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Political Economy of News Media and Journalism
The political economy of news media and journalism critically examines the structures, processes, and democratic role of journalism within society. It is focused on the power relations that shape the production, distribution, and consumption of online ...
Salamon, Errol
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Slow Religion: Literary Journalism as a Tool for Interreligious Dialogue
Religions, 2019 Intercultural and interfaith dialogue is one of the challenges faced by society. In a world marked by globalisation, digitisation, and migratory movements, the media is the agora for people of different faiths and beliefs.
Alba Sabaté Gauxachs +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Politics of Disconnective Media: Unraveling the Materiality of Discourses on Disconnectivity
Media and CommunicationThe commodification of disconnection has attracted growing scholarly attention. Previous research highlighted the instrumentalisation of disconnection for productivity, self-governance, and healthy life. Researchers have also explored the politics of the
Veysel Bozan, Emiliano Treré
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
OLYMPICS Government Response to ‘A London Olympic Bid for 2012’ (HC 268) Report of the Culture, Media and Sport Select Committee Session 2002–2003 [PDF]
, 2003 Document originally hosted on DCMS site: http://www.culture.gov.uk/NR/rdonlyres/C578953D-9618-440B-BF67-B4EE13A3813B/0/OlympicsCm5867.pdf Acknowledged as Crown copyright and used in accordance with Crown copyright policy.Conclusions and recommendations ...
Department For Culture, MAS
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