Results 231 to 240 of about 9,530,044 (407)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Development of selective culture media for efficient isolation of <i>Avibacterium paragallinarum</i> from chickens. [PDF]

open access: yesJ Clin Microbiol
Srednik ME   +7 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Rescue in vitro maturation of germinal vesicle oocytes after ovarian stimulation: the importance of the culture media. [PDF]

open access: yesHum Reprod
Soler N   +8 more
europepmc   +1 more source

Culture Media for Brucella [PDF]

open access: yesJournal of Bacteriology, 1940
Grace P. Kerby, Royall M. Calder
openaire   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

China's new strategy for fighting misconduct in academic journals

open access: yesChinese Medical Journal, 2019
Jian-Ping Lu, Qiang Shi
doaj   +1 more source

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