Results 161 to 170 of about 8,999,056 (423)

Buffering the pH of the culture medium does not extend yeast replicative lifespan

F1000Research, 2013
During chronological aging of budding yeast cells, the culture medium can become acidified, and this acidification limits cell survival. As a consequence, buffering the culture medium to pH 6 significantly extends chronological life span under standard ...
Brian M. Wasko, Daniel T. Carr, Herman Tung, H. Doan, Nathan Schurman, Jillian R Neault, Joey Feng, Janet Lee, B. Zipkin, Jacob Mouser, Edward Oudanonh, Tina C Nguyen, Torin F. Stetina, Anna Shemorry, Mekedes Lemma, M. Kaeberlein   +15 more
semanticscholar   +1 more source

Growth Stimulation of Biological Cells and Tissue by Electromagnetic Fields and Uses Thereof [PDF]

The present invention provides systems for growing two or three dimensional mammalian cells within a culture medium facilitated by an electromagnetic field, and preferably, a time varying electromagnetic field. The cells, and culture medium are contained
Goodwin, Thomas J., Wolf, David A.
core   +1 more source

Impact of the co-culture of Saccharomyces cerevisiae–Oenococcus oenion malolactic fermentation and partial characterization of a yeast-derived inhibitory peptidic fraction [PDF]

, 2010
The present study was aimed to evaluate the impact of the co-culture on the output of malolactic fermentation and to further investigate the reasons of the antagonism exerted by yeasts towards bacteria during sequential cultures.
Mathieu, Florence, Nehme, Nancy, Taillandier, Patricia   +2 more
core   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, Volume 19, Issue 6, Page 1612-1632, June 2025.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, Volume 19, Issue 6, Page 1737-1750, June 2025.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Disentangling Language and Culture for Evaluating Multilingual Large Language Models [PDF]

arXiv
This paper introduces a Dual Evaluation Framework to comprehensively assess the multilingual capabilities of LLMs. By decomposing the evaluation along the dimensions of linguistic medium and cultural context, this framework enables a nuanced analysis of LLMs' ability to process questions within both native and cross-cultural contexts cross-lingually ...
arxiv  

The influence of the surface tension of the culture medium on bacterial growth [PDF]

, 1921
W. P. Larson
openalex   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, Volume 19, Issue 6, Page 1687-1706, June 2025.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Philosophy as a cultural resource and medium of reflection for Hermann Weyl [PDF]

arXiv, 2004
Here we review a kind of post-World-War-II "Nachtrag" to H. Weyl's philosophical comments on mathematics and the natural sciences published in the middle of the 1920s. In a talk given at Z\"urich in the late 1940s, Weyl discussed F.Gonseth's dialectical epistemology and considered it as being restricted too strictly to aspects of historical change. His
arxiv  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source