Results 91 to 100 of about 675,164 (342)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Health System and the Russian Orthodox Church: Prospects for Development [PDF]

open access: yes, 2017
The article examines the participation and assistance of the Orthodox Church in solving problems that allowed to give a scientific justification for the cooperation of health care and Orthodox religious institutions, to determine their role in the ...
Enter Author Name Without Selecting A. Profile: Muhina Natalia, E.   +1 more
core  

Hegel, Reason, and Idealism [PDF]

open access: yes, 1997
In this article I want to focus on the central role that scientific reason plays, for Hegel, in leading us toward idealism, yet its complete failure to adequately establish idealism, and, oddly enough, the way in which this failure turns into a most ...
Kain, Philip J.
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Continuity and Ruptures in Slovak Political Thinking in the Late 19th Century. [PDF]

open access: yesSlovenska Literatura, 2015
The goal of the paper is to present the ideological development of Slovak political thinking in the late 19th century. The framework of the study is built on the journalistic activities of the most significant political thinkers going on in the given ...
Marcel Martinkovič
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Aesthetic functionalism as a principle of literary translation

open access: yesЗаписки з романо-германської філології, 2015
The article deals with the specifics of aesthetic function manifestations in literary translation as seen in linguistic and cultural paradigms of translation studies.
О. В. Ребрій
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Unity and Variety of Musical Culture of The East

open access: yesEurasian music science journal, 2021
About a kind of renaissance of Uzbek (and, in general, the Eastern) music of its active and diverse in the functioning of our era, the explicit updating its stylistic and expressive possibilities. Evidence of this traditional international music festival "Sharq taronalari" (Melodies of the East) held in Samarkand in 1997.
openaire   +2 more sources

PRANOTOCORO AS ONE OF THE SYMBOL OF JAVANESE CULTURE THAT BECOMES DIMINISH FROM DAY TO DAY [PDF]

open access: yes, 2013
Master of ceremony is well known as the representative of the modern person who is directing the ceremony, lead and to work on the list of the ceremony schedule.
Wijaya , Ikha Adhi
core  

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