Results 111 to 120 of about 39,746 (312)
Quality Culture in HigherEducation Institutions
, 2012 The occurrence of trade liberalization in higher education leads us to consider educational standards. In this regard, the institute of higher education has determined to maintain quality assurance and an accountability that can be examined by the public.
Tongsamsi, Isara
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Anniversary bulletin, 1943-1993: Unity Movement 50th year of struggle-and the struggle continues
The Unity Movement was established in 1943 after long and hard struggles of the disfranchised oppressed people in South Africa against foreign domination by first the Dutch and then the British ruling classes. The Non-European Unity Movement (NEUM) as it
New Unity Movement
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Etat d`avancement de la recherche de la production de culture vivreres en Afrique semi-Aride
, 1991 Repor
Organization of African Unity
core
European culture between diversity and unity [PDF]
, 2010 The image of the European culture is given by the association of the concepts people-culture-history-territory, which provides certain local features. From this relation, we identify a cultural area with local, regional and national features beyond a certain European culture.
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
POSTMODERNISMUL – CADRU AL DIVERSITĂŢII EDUCAŢIONALE
Studia Universitatis Moldaviae: Stiinte ale Educatiei, 2010 Postmodernity is the age of thinking, not so much of fragmentation, as of plurality, even the shift from unity to plurality is a form of our existence. Diversity is both an intrinsic attribute of nature and culture. As regards culture, without diversity,
USM ADMIN
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source