Results 101 to 110 of about 675,164 (342)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Culture and Custom in Globalizational Era
Sociological Jurisprudence Journal, 2018 Tradition is one element of the form of culture as the identity of a society. Understanding adat as a form of community culture can accelerate the process of unity and unity of the nation as Indonesia which is composed of various cultures and its ...
I Made Suwitra
doaj
Language, Subjectivity and the Agon: A Comparative Study of Nietzsche and Lyotard [PDF]
, 2015 Political Philosophy and ...
Pearson, James S.
core
, 2013 In 2010 Namibia celebrated its twentieth anniversary of independence from South African rule. The main celebrations in the country's capital Windhoek became the stage for an impressively orchestrated demonstration of maturing nationhood, symbolically ...
Michael Uusiku Akuupa, Godwin Kornes
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Rethinking one`s own culture [PDF]
, 1994 African people reflecting on their own situation will frequently find themselves in a dilemma to identify with western and traditional values. A case study of the Burji (Ethiopia and Kenya) examplifies this.
Amborn, Hermann, Marcus, H. G.
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
The Problem of Religious Tolerance in Kazakhstan: Past and Present
Space and Culture, India, 2018 The problem of the religious tolerance culture that helps to preserve socio-political stability in the society has become a significant theoretical and practical research problem.
Nurlan Balpanov +4 more
doaj +1 more source
Dakwah Dalam Membangun Etika Kerukunan Hidup Umat Beragama [PDF]
, 2015 Indonesia is multi-ethnics, culture and religions,require normative values to regulate social relations.Normative values on religion, social values and moresthat have been prevailing in the community, is thebasis for building a culture of inter-religious
Jasmadi, J. (Jasmadi)
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source