Results 11 to 20 of about 1,484,807 (267)

Using Vertebrate Stem and Progenitor Cells for Cellular Agriculture, State-of-the-Art, Challenges, and Future Perspectives

Biomolecules, 2022
Global food systems are under significant pressure to provide enough food, particularly protein-rich foods whose demand is on the rise in times of crisis and inflation, as presently existing due to post-COVID-19 pandemic effects and ongoing conflict in ...
Teodora Knežić, Ljiljana Janjušević, Mila Djisalov, Supansa Yodmuang, Ivana Gadjanski   +4 more
doaj   +1 more source

HMG-CoA reductase regulation: use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator production in cultured IM-9 cells

Journal of Lipid Research, 1999
The activity of HMG-CoA reductase (HMGR) is tightly regulated, in part through post-transcriptional mechanisms that are mediated by nonsterol products of mevalonate metabolism.
Stephen F. Petras, Saralyn Lindsey, H. James Harwood, Jr.   +2 more
doaj   +1 more source

Design and Validation of Experimental Setup for Cell Spheroid Radiofrequency-Induced Heating

Sensors, 2023
While hyperthermia has been shown to induce a variety of cytotoxic and sensitizing effects on cancer tissues, the thermal dose–effect relationship is still not well quantified, and it is still unclear how it can be optimally combined with other treatment
Ioannis Androulakis, Riccardo Ferrero, Rogier van Oossanen, Alessandra Manzin, Antonia G. Denkova, Kristina Djanashvili, Robin Nadar, Gerard C. van Rhoon   +7 more
doaj   +1 more source

An UPLC-MS/MS Assay to Measure Glutathione as Marker for Oxidative Stress in Cultured Cells

Metabolites, 2019
Oxidative stress plays a role in the onset and progression of a number of diseases, such as Alzheimer’s disease, diabetes and cancer, as well as ageing.
Katharina Herzog, Lodewijk IJlst, Arno G. van Cruchten, Carlo W.T. van Roermund, Wim Kulik, Ronald J. A. Wanders, Hans R. Waterham   +6 more
doaj   +1 more source

Impact Of Phenylpropanoid Compounds On Heat Stress Tolerance In Carrot Cell Cultures

Frontiers in Plant Science, 2016
The phenylpropanoid and flavonoid families include thousands of specialized metabolites that influence a wide range of processes in plants, including seed dispersal, auxin transport, photoprotection, mechanical support and protection against insect ...
Mauro Commisso, Ketti Toffali, Pamela Strazzer, Matteo Stocchero, Stefania Ceoldo, Barbara Baldan, Marisa Levi, Flavia Guzzo   +7 more
doaj   +1 more source

Advances in pharmacological studies of silymarin

Memorias do Instituto Oswaldo Cruz, 1991
Silymarin is the flavonoids extracted from the seeds of Silybum marianum (L) Gearth as a mixture of three structural isomers: silybin, silydianin and silychristin, the former being the most active component. Silymarin protects liver cell membrane against
Yao-Cheng Rui
doaj   +1 more source

The sialic acid binding activity of the S protein facilitates infection by porcine transmissible gastroenteritis coronavirus

Virology Journal, 2011
Background Transmissible gastroenteritis virus (TGEV) has a sialic acid binding activity that is believed to be important for enteropathogenicity, but that has so far appeared to be dispensable for infection of cultured cells. The aims of this study were
Enjuanes Luis, Winter Christine, Bauer Sandra, Schwegmann-Weßels Christel, Laude Hubert, Herrler Georg   +5 more
doaj   +1 more source

Culturing characteristics of Hanwoo myosatellite cells and C2C12 cells incubated at 37°C and 39°C for cultured meat

Journal of Animal Science and Technology, 2023
To improve culture efficiency of Hanwoo myosatellite cells, these cells were cultured at different temperatures. Hanwoo myosatellite cells were compared with C2C12 cells to observe proliferation and differentiation at culture temperatures of 37°C and 39 ...
Sehyuk Oh, Sanghun Park, Yunhwan Park, Yun-a Kim, Gyutae Park, Xiangshun Cui, Kwansuk Kim, Seontea Joo, Sunjin Hur, Gapdon Kim, Jungseok Choi   +10 more
doaj   +1 more source

APOE4 dysregulates autophagy in cultured cells

Autophagy Reports, 2022
Human APOE4 (apolipoprotein E4 isoform) is a powerful genetic risk factor for late-onset Alzheimer disease (AD). Many groups have investigated the effect of APOE4 on the degradation of amyloid β (Aβ), the main component of plaques found in the brains of ...
Gianna M. Fote, Joan S. Steffan
doaj   +1 more source

Long-term imaging of calcium dynamics using genetically encoded calcium indicators and automatic tracking of cultured cells

BioTechniques, 2018
Calcium dynamics is crucial for many signaling pathways and cell functions. Understanding how calcium regulates cell function often requires long-term imaging of calcium dynamics.
Igor Razlivanov, Teresa Liew, Eira Watts Moore, Alaa Al-Kathiri, Tayma Bartram, Dmitriy Kuvshinov, Anton Nikolaev   +6 more
doaj   +1 more source