Results 41 to 50 of about 6,073,818 (310)

Carbachol increases intracellular free calcium concentrations in human granulosa-lutein cells [PDF]

, 1992
We investigated whether the stimulation of human granulosa-lutein cells with muscarinic and nicotinic receptor agonists can cause increases in intracellular free calcium (Ca2+), using Fura-2 microfluorimetry.
Föhr, K. J., Sterzik, K., Gratzl, Manfred, Mayerhofer, Artur   +3 more
core   +1 more source

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells [PDF]

, 2011
High attrition rates of novel anti-cancer drugs highlight the need for improved models to predict toxicity. Although polo-like kinase 1 (Plk1) inhibitors are attractive candidates for drug development, the role of Plk1 in primary cells remains widely ...
Kappel, Sven, Eckhard Wolf, Kreft, B., Martin Bergmann, Martin Klingenspor, Prinz, Florian, Kurunci-Csacsko, Elisabeth, Nicole Sänger, Knecht, R., Jost Seibler, Thure Adler, Florian Prinz, Strebhardt, K., Hrabě de Angelis, M., Busch, D.H., Monika Raab, Sanhaji, Mourad, Yves Matthess, Martin Hrabě de Angelis, Bergmann, M., Adler, Thure, Seibler, Jost, Rathkolb, Birgit, Irene Esposito, Dirk H. Busch, Rathkolb, B., Rozman, J., Rozman, Jan, Esposito, Irene, Yuan, J., Andrea Krämer, Fuchs, H., Calzada-Wack, Julia, Jan Rozman, Rainald Knecht, Esposito, I., Gailus-Durner, Valérie, Hrabé de Angelis, Martin, Knecht, Rainald, Valérie Gailus-Durner, Wolf, E., Prinz, F., Sänger, Nicole, Krämer, A., Calzada-Wack, J., Gailus-Durner, V., Kappel, S., Helmut Fuchs, Kurunci-Csacsko, E., Klingenspor, Martin, Yuan, Juping, Matthess, Yves, Busch, Dirk H., Klaus Strebhardt, Strebhardt, Klaus, Juping Yuan, Kreft, Bertolt, Julia Calzada-Wack, Sven Kappel, Krämer, Andrea, Klingenspor, M., Matthess, Y., Bergmann, Martin, Birgit Rathkolb, Adler, T., Elisabeth Kurunci-Csacsko, Sänger, N., Raab, Monika, Bertolt Kreft, Fuchs, Helmut, Wolf, Eckhard, Mourad Sanhaji, Raab, M., Sanhaji, M., Seibler, J.   +74 more
core   +1 more source

Characterization of cells of amniotic fluids by immunological identification of intermediate-sized filaments: Presence of cells of different tissue origin [PDF]

, 1981
Antibodies against intermediate-sized filaments, of the prekeratin or vimentin type, were used to investigate the presence of these filaments by indirect immunofluorescence microscopy in cultured and non-cultured amniotic fluid cells, in frozen sections ...
Cremer, Thomas, Treiss, I., Cremer, Marion, Franke, W. W., Hager, D.   +4 more
core   +1 more source

In vitro study on the mechanisms of action of a novel phytotherapeutic compound against human hepatoma cells

Annals of Hepatology, 2007
HepG2 human hepatoma cells were incubated for 24 or 48 h with various concentrations of YHK solution. After 24 h incubation, cell proliferation and cytotoxicity were determined by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl ...
Francesco Marotta, Masatoshi Harada, Khean-Lee Goh, Aldo Lorenzetti, Paolo Marandola, Emilio Minelli   +5 more
doaj   +1 more source

Introduction of Macromolecules into Bovine Adrenal Medullary Chromaffin Cells and Rat Pheochromocytoma Cells (PC12) by Permeabilization with Streptolysin O: Inhibitory Effect of Tetanus Toxin on Catecholamine Secretion [PDF]

, 1989
Conditions are described for controlled plasma membrane permeabilization of rat pheochromocytoma cells (PC12) and cultured bovine adrenal chromaffin cells by Streptolysin O (SLO).
Ahnert-Hilger, G., Gratzl, Manfred, Bader, M. F., Bhakdi, S.   +3 more
core   +1 more source

Fibrin gel as a scaffold for skin substitute – production and clinical experience

Acta Clinica Croatica, 2016
The purpose of this study was to create a fibrin-based human skin substitute in vitro with epidermal and dermal component and to assess its healing potential in deep partial and full thickness burns.
Antun Kljenak, Mirna Tominac Trcin, Marina Bujić, Tamara Dolenec, Martina Jevak, Gordan Mršić, Gordana Zmiš, Zoran Barčot, Ante Muljačić, Maja Popović   +9 more
doaj   +1 more source

Three dimensional neuronal cell cultures more accurately model voltage gated calcium channel functionality in freshly dissected nerve tissue. [PDF]

PLoS ONE, 2012
It has been demonstrated that neuronal cells cultured on traditional flat surfaces may exhibit exaggerated voltage gated calcium channel (VGCC) functionality.
Yinzhi Lai, Ke Cheng, William Kisaalita
doaj   +1 more source

CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes [PDF]

, 2014
Standard culture of human induced pluripotent stem cells (hiPSCs) requires basic Fibroblast Growth Factor (bFGF) to maintain the pluripotent state, whereas hiPSC more closely resemble epiblast stem cells than true naïve state ES which requires LIF to ...
Tang, D, Suzuki, H., Forrest, Alistair R. R., Hasegawa, Y., Suzuki, H, Ovchinnikov, Dmitry A., Hitchens, Kelly J., Takahashi, N., Forrest, A.R.R., Kenna, Tony, Suzuki, Harukazu, Tang, D., Joshi, Anagha, Hayashizaki, Y., Wolvetang, Ernst, Tang, Dave, Suzuki, H., Forrest, Alistair R R, FANTOM Consortium, the FANTOM consortium, Vijayan, Dipti, Wells, Christine A., Hasegawa, Y, Hayashizaki, Yoshihide, Forrest, ARR, Takahashi, Naoko, Briggs, James, Hasegawa, Yuki, Blumenthal, Antje, Tang, D., Hayashizaki, Y, ?, ?, Sajantila, Antti, Hasegawa, Y., Takahashi, N, Takahashi, N., Forrest, A. R., Beckhouse, Anthony G., FANTOM Consortium,, Hayashizaki, Y.   +39 more
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]

, 1987
Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger, G., Manfred Gratzl, Gratzl, Manfred, Gudrun Ahnert‐Hilger   +3 more
core   +1 more source