Results 71 to 80 of about 1,180,431 (244)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An R Implementation of the Polya-Aeppli Distribution [PDF]

open access: yes, 2014
An efficient implementation of the Polya-Aeppli, or geometirc compound Poisson, distribution in the statistical programming language R is presented.
Burden, Conrad J.
core  

Distribution function in quantal cumulant dynamics [PDF]

open access: yesThe Journal of Chemical Physics, 2008
We have derived a quantum distribution function in terms of cumulants that are expectation values of a (anti)symmetric-ordered product of position and momentum fluctuation operators. A second-order approximation leads a Gaussian distribution function, which is positive definite and has proper marginals so that the Shannon entropy can be evaluated.
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Wind Turbine Power Curves Based on the Weibull Cumulative Distribution Function

open access: yesApplied Sciences, 2018
The representation of a wind turbine power curve by means of the cumulative distribution function of a Weibull distribution is investigated in this paper, after having observed the similarity between such a function and real WT power curves. The behavior
Neeraj Bokde   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Image Feature Extraction Using Symbolic Data of Cumulative Distribution Functions

open access: yesMathematics
Symbolic data analysis is an emerging field in statistics with great potential to become a standard inferential technique. This research introduces a new approach to image feature extraction using the empirical cumulative distribution function (ECDF) and
Sri Winarni   +3 more
doaj   +1 more source

Exactly solvable tight-binding model on the RAN: fractal energy spectrum and Bose-Einstein condensation

open access: yes, 2014
We initially consider a single-particle tight-binding model on the Regularized Apollonian Network (RAN). The RAN is defined starting from a tetrahedral structure with four nodes all connected (generation 0).
Serva, Maurizio
core   +1 more source

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