Results 41 to 50 of about 320,148 (243)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Stochastic Dominance Analysis for the Poverty in Tabalong Regency 2013 and 2017

open access: yesJurnal Bina Praja, 2018
Although its issue could be addressed from of various perspectives over the years, poverty is the object of the government’s policy programs to be alleviated since the Indonesian independence. With the advancement of technology and science in the recent
Ahmadi Murjani
doaj   +1 more source

Poly-Weighted Exponentiated Gamma Distribution with Application

open access: yesJournal of Statistical Theory and Applications (JSTA), 2020
This paper proposes a weighting of the exponentiated gamma distribution with a polynomial function called the poly-weighted exponentiated gamma distribution (PWEGD).
E. B. Nkemnole, E. M. Ikegwu
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Fractional Cumulative Residual Mean Relative Entropy and Its Application in an Aeroengine Gas Path System

open access: yesFractal and Fractional, 2023
Mean relative entropy has a wide range of applications in measuring information differences. However, relative entropy is difficult to approximate from empirical distribution entropy.
Keqiang Dong, Shushu Li
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Exact Results for the Distribution of Randomly Weighted Sums

open access: yesMathematics
Dependent random variables play a crucial role in various fields, from finance and statistics to engineering and environmental sciences. Often, interest lies in understanding the aggregate sum of a collection of dependent variables with random weights ...
Thomas Hitchen, Saralees Nadarajah
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Closed-Form Cubic–Logistic Approximation to the Normal Cumulative Distribution Function

open access: yesMathematics
Accurate evaluation of the standard normal cumulative distribution function is fundamental in many areas of mathematics, statistics, and applied computation, yet no closed-form expression in elementary functions exists.
Michael Arnold Frölich
doaj   +1 more source

Error Probability Analysis of a Composite Weibull/Log-Normal Fading Channel

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi, 2019
In this study, error probability of a single-input single-output (SISO) system is investigated over a composite Weibull/log-normal fading channel. We aim to study a SISO system in the composite Weibull/log-normal composite fading model which is useful in
Mehmet BİLİM
doaj   +1 more source

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