Results 111 to 120 of about 8,217,055 (263)

Kaplan–Meier curves for good live birth and live birth.

, 2022
Good live birth rate is shown according to treatment group in panel A, and live birth rate is shown in panel B. (TIF)
Christos Coutifaris (245252), Esther Eisenberg (10641324), Kurt T. Barnhart (2172793), David B. Sarwer (11965012), Karl R. Hansen (7052144), Jennifer Mersereau (11965006), Penny M. Kris-Etherton (11965009), Marcelle I. Cedars (11964991), Rebecca Usadi (11492379), Richard S. Legro (8086748), Kathleen M. Hoeger (11964994), Anne Z. Steiner (11964988), Erica B. Johnstone (11964997), Heping Zhang (29038), Nanette Santoro (2746333), J. C. Trussell (7052147), Robert A. Wild (11965003), Michael P. Diamond (8273985), Hao Huang (111923), Daniel J. Haisenleder (11965000), Stephen A. Krawetz (8273988)   +20 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Cumulative live birth rate in different subject groups classified according to the quartile of serum AMH and AFC.

, 2014
Values are expressed in median (interquartile range).a p = 0.012 (statistically significant, Fisher's Exact test).b p = 0.026 (statistically significant, Fisher's Exact test).c p = 0.002 (statistically significant, Fisher's Exact test).d p = 0.0497 ...
Estella Yee Lan Lau (405995), William Shu Biu Yeung (405996), Hang Wun Raymond Li (405993), Ernest Hung Yu Ng (405998), Vivian Chi Yan Lee (405994), Pak Chung Ho (405997)   +5 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Cumulative live birth rates in women with endometriosis undergoing ART treatment

Human Reproduction
Abstract STUDY QUESTION How do cumulative live birth rates (CLBRs) in women with endometriosis compare to those with other infertility diagnoses undergoing ART? SUMMARY ANSWER Women with endometriosis as the sole ...
Repon C Paul, Rebecca Deans, Amanda Henry, Cecilia Ng, Ingrid Rowlands, Gita D Mishra, Jason Abbott, Georgina M Chambers   +7 more
openaire   +5 more sources

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Impact of maternal physical activity on outcome of assisted reproduction

Frontiers in Endocrinology
IntroductionThe influence of physical activity on outcomes of assisted reproductive technology (ART) remains incompletely understood, with conflicting evidence regarding the impact of exercise intensity and frequency.
James Geiger, Alexander Quaas, Philipp Quaas, Andreas Schötzau, Viola Heinzelmann-Schwarz, Ursula Gobrecht-Keller, Manuel Fischer   +6 more
doaj   +1 more source