Results 91 to 100 of about 8,217,055 (263)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Patient-reported menstrual and obstetric outcomes following hysteroscopic adhesiolysis for Asherman syndrome

F&S Reports, 2021
Objective: Review the menstrual and obstetric outcomes among Asherman syndrome patients when stratified by disease severity. Design: Retrospective cohort study.
Blanca Morales, M.D., Peter Movilla, M.D., Joyce Wang, B.A., Jennifer Wang, M.S., Alexandria Williams, M.D., Tammy Chen, B.S., M.P.H., Himabindu Reddy, M.D., Jovana Tavcar, M.D., Megan Loring, M.D., Stephanie Morris, M.D., Keith Isaacson, M.D.   +10 more
doaj   +1 more source

Lifestyle intervention prior to IVF does not improve embryo utilization rate and cumulative live birth rate in women with obesity: a nested cohort study

Human Reproduction Open, 2021
STUDY QUESTION Does lifestyle intervention consisting of an energy-restricted diet, enhancement of physical activity and motivational counseling prior to IVF improve embryo utilization rate (EUR) and cumulative live birth rate (CLBR) in women with ...
Zheng Wang, H. Groen, K. V. van Zomeren, A. Cantineau, A. V. van Oers, A. V. van Montfoort, W. Kuchenbecker, M. J. Pelinck, F. Broekmans, N. Klijn, E. Kaaijk, B. Mol, A. Hoek, J. Van Echten-Arends   +13 more
semanticscholar   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Development and validation of a clinical nomogram for predicting cumulative live birth rate in ovarian endometrioma patients undergoing ethanol sclerotherapy and in vitro fertilization/intracytoplasmic sperm injection

Frontiers in Endocrinology
BackgroundEffective individualized tools to predict cumulative live birth rates are lacking for patients with ovarian endometriomas undergoing In Vitro Fertilization or Intracytoplasmic Sperm Injection after ultrasound-guided ethanol sclerotherapy.
Bowen Liu, Yamei Li, Qian Zhou, Feng Wang, Shuping Liu, Chahui Zhang, Jinjiang Huang, Weifen Deng, Yuhua Shi   +8 more
doaj   +1 more source

Comparison of IVF/ICSI outcomes in advanced reproductive age patients with polycystic ovary syndrome and advanced reproductive age normal controls: a retrospective cohort study

BMC Pregnancy and Childbirth, 2023
Background At present, there are few studies on whether there is reproductive advantage in advanced polycystic ovary syndrome (PCOS) patients, and the existing research results are also controversial.
Xing Zhang, Fang Lian, Danqi Liu
doaj   +1 more source

Comparison of Cumulative Live Birth Rate Between Aged PCOS Women and Controls in IVF/ICSI Cycles

Frontiers in Endocrinology, 2021
The present study aimed to assess whether women with polycystic ovarian syndrome (PCOS) ≥35 years age undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles experienced a higher cumulative live birth rate (CLBR) over a two-
Zhuo-Yao Mai, Manlin Liu, P. Pan, Lin Li, Jia Huang, Xiao-Li Chen, Dong-Zi Yang   +6 more
semanticscholar   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Association between female waist-hip ratio and live birth in patients undergoing in vitro fertilization: a retrospective cohort study

Frontiers in Endocrinology
BackgroundMaternal obesity is associated with adverse pregnancy outcomes. It negatively affects IVF/ICSI outcomes and offspring health. However, it is unclear whether waist-hip ratio (WHR) has an impact on outcomes of in vitro fertilization (IVF) or ...
Mingming Ye, Yingying Yang, Chenting Cai, Zhen Li, Andong Qiu, Jia He, Jing Ma, Orhan Bukulmez, Robert J. Norman, Xiaoming Teng, Miaoxin Chen   +10 more
doaj   +1 more source

Comparison of pregnancy outcomes between GnRH antagonist protocol with freeze-all strategy and long-acting GnRH agonist protocol in women with adenomyosis undergoing IVF/ICSI: a propensity-score matching analysis

BMC Pregnancy and Childbirth, 2022
Background Plenty of studies explored the most optimal treatment protocol for infertile women with adenomyosis in in-vitro fertilization (IVF) /intracytoplasmic sperm injection (ICSI), however, there is still no consensus on which treatment protocol is ...
Liting Zhang, He Cai, Xitong Liu, Yao Xiong, Xiaoling Liang, Juanzi Shi   +5 more
doaj   +1 more source