Results 81 to 90 of about 50,172 (268)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Resolved hyperthyroidism before IVF is not associated with improved cumulative live birth rates: a retrospective cohort study

Frontiers in Endocrinology
BackgroundHyperthyroidism adversely impacts female reproduction, yet its association with in vitro fertilization (IVF) outcomes remains controversial. It remains unknown whether ovarian function recovers upon achieving euthyroidism.
Huizi Jin, Jiejun Luo, Menglu Wu, Yuxuan Fang, Zijin Xu, Lin Zhu, Mingzhu Cao, Zhu Liang, Jing Wang, Yanshan Lin, Yixuan Wu, Wenju Peng, Wenju Peng, Haiying Liu, Jian-Qiao Liu   +14 more
doaj   +1 more source

Hysteroscopic resection of type 3 fibroids could improve the pregnancy outcomes in infertile women: a case–control study

BMC Pregnancy and Childbirth, 2022
Background Type 3 fibroids are a special subtype of intramural fibroids that are likely to affect the pregnancy outcomes of assisted reproductive techniques.
Ying Han, Ruqiang Yao, Yinfeng Zhang, Zexin Yang, Haining Luo, XinYan Wang, Aijun Du, Yunshan Zhang, Yingjun Zhu   +8 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Cumulative live birth rates in women with endometriosis undergoing ART treatment

Human Reproduction
Abstract STUDY QUESTION How do cumulative live birth rates (CLBRs) in women with endometriosis compare to those with other infertility diagnoses undergoing ART? SUMMARY ANSWER Women with endometriosis as the sole ...
Repon C Paul, Rebecca Deans, Amanda Henry, Cecilia Ng, Ingrid Rowlands, Gita D Mishra, Jason Abbott, Georgina M Chambers   +7 more
openaire   +5 more sources

The combined impact of maternal age and body mass index on cumulative live birth following in vitro fertilization.

, 2019
BACKGROUND: It is critical to evaluate the combined impact of age and body mass index on the cumulative likelihood of live birth following in vitro fertilization, as achieving a lower body mass index before infertility treatment often is recommended for ...
Farland, L. V., Ginsburg, E. S., Goldman, R. H., Zera, C. A., Thomas, A. M.   +4 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Cumulative live birth rate of advanced-age women more than 40 with or without poor ovarian response

, 2019
Objective: The aim of this study was to investigate cumulative live birth rate (CLBR) per oocyte retrieval cycle and per patient in women over 40 years old undergoing IVF/ICSI treatments, stratified for age, ovarian response and oocyte retrieval cycle ...
Cunli Wang, Ruibing He, Huiqun Yin, Jie Zhu, Zhenyi Cao, Hong Jiang   +5 more
core   +1 more source

Time-lapse technology improves total cumulative live birth rate and shortens time to live birth as compared to conventional incubation system in couples undergoing ICSI

, 2021
International audiencePurpose: The improvement of clinical outcome provided by time-lapse technology (TLT) in IVF over conventional incubation (CI) still remains controversial.
Loubersac, Sophie, Barriere, Paul, Lefebvre, Tiphaine, Lammers, Jenna, Freour, Thomas, Reignier, Arnaud   +5 more
core   +1 more source