Results 61 to 70 of about 5,852,482 (292)

Trapezoidal Intuitionistic Fuzzy Multiattribute Decision Making Method Based on Cumulative Prospect Theory and Dempster-Shafer Theory

open access: yesJournal of Applied Mathematics, 2014
With respect to decision making problems under uncertainty, a trapezoidal intuitionistic fuzzy multiattribute decision making method based on cumulative prospect theory and Dempster-Shafer theory is developed.
Xihua Li, Fuqiang Wang, Xiaohong Chen
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating Consumer Participation Decision in Community-Supported Agriculture: An Application of Cumulative Prospect Theory

open access: yesJournal of Agricultural and Resource Economics, 2020
Using the framework of cumulative prospect theory (CPT), we investigate consumers' decision to participate in community-supported agriculture (CSA) under risk and uncertainty.
Shuoli Zhao, Chengyan Yue
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Research on Decision-Making Behavior of Discretionary Lane-Changing Based on Cumulative Prospect Theory

open access: yesJournal of Advanced Transportation, 2020
In this paper, the decision-making model of discretionary lane-changing is established using cumulative prospect theory (CPT). Through analyzing the vehicles’ dynamic running states, safety spacing calculating approaches for discretionary lane-changing ...
Xueqin Long   +3 more
doaj   +1 more source

Cumulative prospect theory and mean–variance analysis: a rigorous comparison [PDF]

open access: yesJournal of Computational Finance, 2014
We propose a numerical optimization approach that can be used to solve portfolio selection problems including several assets and involving objective functions from cumulative prospect theory (CPT). Implementing the suggested algorithm, we compare asset allocations that are derived for CPT based on two different methods: maximizing CPT along the mean ...
Hens, Thorsten, Mayer, Janos
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

BEHAVIORAL ASPECTS IN INSURANCE MARKET [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2013
The insurance industry has an essential economic importance.In spite of the great progress,we have to emphase that the existing theoretic models cannot entirely explain the mechanism of the insurance market and of its decisional process,especially in ...
Stroe Andreea, , ,
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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