Results 61 to 70 of about 171,696 (334)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

An experimental study on cumulative prospect theory learning model of travelers’ dynamic mode choice under uncertainty

open access: yesInternational Journal of Transportation Science and Technology, 2017
In this paper, we examined travelers’ dynamic mode choice behavior under travel time variability. We found travelers’ inconsistent risk attitudes through a binary mode choice experiment.
Chao Yang   +3 more
doaj   +1 more source

Cumulative Prospect Theory for Parametric and Multiattribute Utilities [PDF]

open access: yesMathematics of Operations Research, 2001
Different attitudes towards gains and losses are a prominent feature of cumulative prospect theory for decision under uncertainty. In particular, decision weights for uncertain events can depend on whether the events involve gains or losses, and the shape of the utility function can reveal loss aversion.
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cumulative Prospect Theory-Driven Pigeon-Inspired Optimization for UAV Swarm Dynamic Decision-Making

open access: yesDrones
To address the dynamic decision-making and control problem in unmanned aerial vehicle (UAV) swarms, this paper proposes a cumulative prospect theory-driven pigeon-inspired optimization (CPT-PIO) algorithm. Gray relational analysis and information entropy
Yalan Peng, Mengzhen Huo
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Estimation of the Utility Function of Money and Housing Based on the Cumulative Prospect Theory

open access: yesReal Estate Management and Valuation, 2023
This article addresses the issue of the utility of money and the utility of housing with a value equivalent to that amount of money. The literature provides many reports on the shape of the utility function for money, but much less research has been ...
Justyna Brzezicka, M. Tomal
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

New tests of cumulative prospect theory and the priority heuristic [PDF]

open access: yesJudgment and Decision Making, 2008
Previous tests of cumulative prospect theory (CPT) and of the priority heuristic (PH) found evidence contradicting these two models of risky decision making. However, those tests were criticized because they had characteristics that might ``trigger'' use
Michael H. Birnbaum
doaj  

Decision-making under Risk: A Ship Sale and Purchase Problem by Utilizing Cumulative Prospect Theory

open access: yesJournal of Eta Maritime Science, 2022
Decision-making is often performed intuitively, yet formal decision-making by logical reasoning is needed for crosschecking or advocating despite its being burdensome and comprehensive.
Aytek Güngör, Barış Barlas
doaj   +1 more source

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