Results 71 to 80 of about 2,302 (200)

A Microbial Transformation Model for Simulating Mammal Metabolism of Artemisinin

open access: yesMolecules, 2019
Artemisinin (ART) is a highly effective antimalarial agent isolated from the traditional Chinese herb Qinghao. Metabolism of ART and its derivatives in the body is one of the most pressing issues for pharmaceutical scientists.
Yue Ma   +7 more
doaj   +1 more source

Papaverinol-N-Oxide: A Microbial Biotransformation Product of Papaverine with Potential Antidiabetic and Antiobesity Activity Unveiled with In Silico Screening

open access: yesMolecules, 2023
Bioconversion of biosynthetic heterocyclic compounds has been utilized to produce new semisynthetic pharmaceuticals and study the metabolites of bioactive drugs used systemically.
Duaa Eliwa   +8 more
doaj   +1 more source

Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

open access: yesFood Science &Nutrition, Volume 13, Issue 7, July 2025.
Mushrooms are highly nutritious, packed with vitamins, minerals, antioxidants, essential amino acids, and bioactive compounds. They offer various health benefits, including boosting immunity, reducing inflammation, and supporting gut and cardiovascular health. Rich in carbohydrates, quality protein, essential fatty acids, and both soluble and insoluble
Solomon Fitsum   +2 more
wiley   +1 more source

Transformation of 1- and 2-methylnaphthalene by Cunninghamella elegans [PDF]

open access: yesApplied and Environmental Microbiology, 1984
Cunninghamella elegans metabolized 1- and 2-methylnaphthalene primarily at the methyl group to form 1- and 2-hydroxymethylnaphthalene, respectively. Other compounds isolated and identified were 1- and 2-naphthoic acids, 5-hydroxy-1-naphthoic acid, 5-hydroxy-2-naphthoic acid, 6-hydroxy-2-naphthoic acid, and phenolic derivatives of 1- and 2 ...
C E, Cerniglia   +3 more
openaire   +2 more sources

Commodity risk assessment of Betula pendula and Betula pubescens plants from the UK

open access: yesEFSA Journal, Volume 22, Issue 11, November 2024.
Abstract The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’. This Scientific Opinion covers plant health risks posed by plants of Betula pendula and B.
EFSA Panel on Plant Health (PLH)   +32 more
wiley   +1 more source

Biotransformation of hydroxychloroquine to evaluate the cytotoxicity of its metabolites and mimic mammalian metabolism

open access: yesResults in Chemistry, 2023
Hydroxychloroquine (HCQ) displays attractive anti-inflammatory and antiviral effects. Because of that, such a drug made part of some clinical trials for combating Sars-CoV-2 during the COVID-19 pandemic.
Valmore Henrique Pereira dos Santos   +4 more
doaj   +1 more source

A stable backbone for the fungi [PDF]

open access: yes, 2009
Fungi are abundant in the biosphere. They have fascinated mankind as far as written history goes and have considerably influenced our culture. In biotechnology, cell biology, genetics, and life sciences in general fungi constitute relevant model ...
Anne Kupczok   +7 more
core   +1 more source

Skin mucormycosis presenting as an erythema-nodosum-like rash in a renal transplant recipient: a case report [PDF]

open access: yes, 2008
Introduction Cutaneous mucormycosis is a rare entity related to kidney transplantation. It usually presents with ecthyma-like lesions and black necrotic cellulitis.
Nader Nouri-Majalan   +16 more
core   +1 more source

Synthesis and Analysis of (γ,γ’,γ’’‐Trifluoro)neopentyl (TFNP) Aryl Ethers as a Polar Fluoroaliphatic Motif

open access: yesChemistry – A European Journal, Volume 30, Issue 57, October 11, 2024.
(γ,γ’,γ’’‐Trifluoro)neopentyl (TFNP) aryl ethers are prepared as a new motif from tosylate 3. The motif has a preferred ‘propellar’ conformation which can adopt left or right handed twists. LogP's are lower than tert‐butyl analogues. Interactions between TFNP groups in the solid state are shown to also anchor supramolecular architectures.
Atsushi Tarui   +9 more
wiley   +1 more source

Comprehensive Metabolic Profiling of Euphorbiasteroid in Rats by Integrating UPLC-Q/TOF-MS and NMR as Well as Microbial Biotransformation

open access: yesMetabolites, 2022
Euphorbiasteroid, a lathyrane-type diterpene from Euphorbiae semen (the seeds of Euphorbia lathyris L.), has been shown to have a variety of pharmacological effects such as anti-tumor and anti-obesity.
Sijia Xiao   +10 more
doaj   +1 more source

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