Results 31 to 40 of about 537 (173)

Human IgE Antibodies Recognize the Vicilin and Alpha‐Hairpinin Domains of Peanut Allergen Ara h 1

Allergy, EarlyView.
The ɑ‐hairpinin of Ara h 1 contains a dominant epitope that is both frequently recognized and blocks a majority of the IgE against this domain. Including this region in tests may improve diagnosis of peanut allergy. The trimeric structure of the vicilin region explains the ability of Ara h 1 to induce anaphylaxis with a single antibody.
Taylor M. Cosey, Gage O. Leighton, Emmanuel R. De Diavoukana, Min Shi, Alexander C. Y. Foo, Anna Pomés, Jacqueline B. Nesbit, Stephen A. Y. Gipson, Paige Creeks, Jian Zhang, R. Stokes Peebles, Soheila J. Maleki, Derek Croote, Scott A. Smith, Geoffrey A. Mueller   +14 more
wiley   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

Mechanistic Insights into Dimethylsulfoniopropionate Lyase DddY, a New Member of the Cupin Superfamily [PDF]

Journal of Molecular Biology, 2017
The marine osmolyte dimethylsulfoniopropionate (DMSP) is one of Earth's most abundant organosulfur molecules. Bacterial DMSP lyases cleave DMSP, producing acrylate and dimethyl sulfide (DMS), a climate-active gas with roles in global sulfur cycling and atmospheric chemistry. DddY is the only known periplasmic DMSP lyase and is present in β-, γ-, δ- and
Li, Chun-Yang, Zhang, Dian, Chen, Xiu-Lan, Wang, Peng, Shi, Wei-Ling, Li, Ping-Yi, Zhang, Xi-Ying, Qin, Qi-Long, Todd, Jonathan D., Zhang, Yu-Zhong   +9 more
openaire   +4 more sources

Cross‐species transcriptomics uncovers shared responses to water deficiency in plants

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract Deepening our knowledge of conserved molecular mechanisms governing stress responses in plants is fundamental for identifying new core genes and processes involved in tolerance to adverse environmental conditions. For this purpose, we developed a bioinformatic pipeline to retrieve and integrate stress‐related RNA‐seq transcriptomic data from ...
Francesco Punzi, Diana Lucia Zuluaga, Qiao Wen Tan, Marek Mutwil, Gabriella Sonnante, Pasquale Luca Curci   +5 more
wiley   +1 more source

Sequence Analysis of the Cupin Gene Family in Synechocystis PCC6803 [PDF]

Microbial & Comparative Genomics, 1998
The recently described cupin superfamily of proteins includes the germin and germinlike proteins, of which the cereal oxalate oxidase is the best characterized. This superfamily also includes seed storage proteins, in addition to several microbial enzymes and proteins with unknown function.
openaire   +2 more sources

Modeling the Metal Binding Site in Cupin Proteins [PDF]

, 2011
The name for cupin proteins is derived from the Latin term for small barrel, ‘Cupa’. Proteins that belong to the group of cupins adopt a barrel-like structure (Dunwell et al., 2001). According to the database of Structural Classification of Proteins (SCOP) (Murzin et al., 1995), the cupin proteins have been classified as members of ‘RmlC-like Cupins ...
Ferman A., Atanu Banerjee, Bojan Sljivic
openaire   +1 more source

Meroterpenoids Produced by Fungi: Occurrence, Structural Diversity, and Biological Activity (An Update: February 2020 to December 2025)

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang, Jinqin Wei, Zhao Jiang, Yingming Luo, Yan Zhou, Jiafan Yang, Hui Cui   +6 more
wiley   +1 more source

Resistência Natural de Eucalyptus urophylla e Corymbia citriodora à Coptotermes gestroi (Isoptera; Rhinotermitidae) em Laboratório [PDF]

Floresta e Ambiente
RESUMO Este trabalho teve como objetivo avaliar a resistência natural da madeira de Eucalyptus urophylla e Corymbia citriodora ao ataque de Coptotermes gestroi. A avaliação da resistência a cupins foi realizada segundo a norma ASTM D - 3345 (American...,
Rodrigo Bastos Rodrigues, Edvá Oliveira Brito   +1 more
doaj   +1 more source

Densidade e distribuição vertical de Macroinvertebrados em solos argilosos e arenosos na Amazônia Central [PDF]

Acta Amazonica, 1998
A densidade e a distribuição vertical da macrofauna do solo foram estudadas nas estações chuvosa e seca na região de Manaus, Estado do Amazonas, Brasil, sob três tipos de cobertura vegetal, em áreas de solo arenoso e de solo argiloso, durante dois anos ...
Adelmar G BANDEIRA, Ana Y HARADA
doaj   +1 more source

Single‐Cell Transcriptomics Reveals the FA9–VAP Module Regulating Fatty Acid Accumulation in Soybean Seeds

Plant Biotechnology Journal, Volume 24, Issue 11, Page 5812-5829, November 2026.
ABSTRACT As a major commercial legume crop, soybean ranks among the world's most significant sources of edible oil and plant protein. We previously identified a SEIPIN homologue (FA9) at the fatty acid 9 locus that promotes fatty acid accumulation in soybean.
Hui Li, Tianshu Li, Xiaorui Xu, Jinhang Cui, Xin Chen, Jingyi Huang, Jia Song, Cui Mu, Xinyu Hong, Chunyan Liu, Ning Wang, Xue Han, Sui Wang, Qingshan Chen, Zhaoming Qi   +14 more
wiley   +1 more source