Results 101 to 110 of about 68,623 (278)

A colony provides a safe haven [PDF]

open access: yes
For the Contingency of Curation conference we explored new ways of presenting the traditional paper to a conference by creating a sound work. The original content of the presentation was Host Artists Group (H.A.G.) text* written for S.H.U.'s Transmission
Webb, Neil, Wright, Ron
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Vladivostok Installations: On the Problem of Studying Contemporary Digital Art

open access: yesУправление культурой
This article explores the complex issues of exhibiting and perceiving digital art at the beginning of the 21st century, using Vladivostok's artistic practice as a case study.
Ekaterina D. Megid
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

‘A material influence imperceptibly exercised on the taste and judgement of the public’: The Burlington Fine Arts Club and the history of collecting [PDF]

open access: yesJournal of Art Historiography, 2019
Founded in 1866 by the South Kensington curator John Charles Robinson, the Burlington Fine Arts Club played a critical role in the landscape of collecting and display over its near century long history.
Eloise Donnelly
doaj  

Education alignment [PDF]

open access: yes, 2012
This essay reviews recent developments in embedding data management and curation skills into information technology, library and information science, and research-based postgraduate courses in various national contexts.
Corrall, S.   +3 more
core   +2 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Playing at the crossroads [PDF]

open access: yes, 2013
Objectives; The Design Research Group (DRG) at The University of Northampton has been engaged in a number of Knowledge Transfer Partnerships (KTP). Three of these KTP's have involved designing toys, games and playthings. The first exhibition's aim was to
Thomas, Vicki
core  

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