Results 131 to 140 of about 213,267 (396)

Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review

open access: yesMolecules, 2020
Todays, nano-pharmaceutics is emerging as an important field of science to develop and improve efficacy of different drugs. Although nutraceuticals are currently being utilized in the prevention and treatment of various chronic diseases such as cancers ...
Mahshid Moballegh Nasery   +9 more
semanticscholar   +1 more source

Scale-Up Synthesis and In Vivo Anti-Tumor Activity of Curcumin Diethyl Disuccinate, an Ester Prodrug of Curcumin, in HepG2-Xenograft Mice

open access: yesPharmaceutics, 2019
Previously, we synthesized curcumin and a succinate ester prodrug of curcumin namely curcumin diethyl disuccinate (CurDD) in the lab scale, which yielded hundred milligrams to few grams of the compounds.
Chawanphat Muangnoi   +7 more
doaj   +1 more source

Sustained proliferation in cancer: mechanisms and novel therapeutic targets [PDF]

open access: yes, 2015
Proliferation is an important part of cancer development and progression. This is manifest by altered expression and/or activity of cell cycle related proteins.
Abdelwahab   +744 more
core   +2 more sources

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

open access: yesAdvanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang   +9 more
wiley   +1 more source

A multi-targeted approach to suppress tumor-promoting inflammation [PDF]

open access: yes, 2015
Cancers harbor significant genetic heterogeneity and patterns of relapse following many therapies are due to evolved resistance to treatment. While efforts have been made to combine targeted therapies, significant levels of toxicity have stymied efforts ...
Abbas K. Samadi   +873 more
core   +1 more source

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

open access: yesAdvanced Science, EarlyView.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou   +17 more
wiley   +1 more source

Curcumin inhibits the replication of enterovirus 71 in vitro

open access: yesActa Pharmaceutica Sinica B, 2014
Human enterovirus 71 (EV71) is the main causative pathogen of hand, foot, and mouth disease (HFMD) in children. The epidemic of HFMD has been a public health problem in Asia-Pacific region for decades, and no vaccine and effective antiviral medicine are ...
Ying Qin   +13 more
doaj   +1 more source

Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease

open access: yesAggregate, EarlyView.
This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang   +4 more
wiley   +1 more source

Encapsulation in lysozyme/A. Sphaerocephala Krasch polysaccharide nanoparticles increases stability and bioefficacy of curcumin

open access: yesJournal of Functional Foods, 2017
A facile approach to fabricate nanoparticles (NPs) via self-assembly of lysozyme (Ly) and purified Artemisia sphaerocephala Krasch seed polysaccharide (ASKP-3) was developed for the first time to encapsulate and protect curcumin.
Daoyuan Ren   +5 more
doaj  

Synthesis of Metal–Curcumin Complex Compounds (M = Na⁺, Mg²⁺, Cu²⁺)

open access: yesJurnal Kimia Sains dan Aplikasi, 2020
Curcumin complex compound, MLn (L = curcumin; M = Na+, Mg2+, Cu2+) has been synthesized from the reaction between curcumin and metal precursors (NaCl, MgSO4.7H2O, CuCl2.2H2O) in ethanol under reflux conditions.
Peni Peni   +2 more
doaj   +1 more source

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