Results 171 to 180 of about 213,267 (396)

The potential for dietary factors to prevent or treat osteoarthritis [PDF]

open access: yes, 2014
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping   +8 more
core   +1 more source

Exploring the potential of curcumin-loaded PLGA nanoparticles for angiogenesis and antioxidant proficiency in zebrafish embryo (Danio rerio)

open access: yesFuture Journal of Pharmaceutical Sciences
Background Curcumin is an age old traditional medicine. Although curcumin has several advantages, its water solubility and bioavailability limit its use as a natural therapeutic agent.
Achinta Singha   +7 more
doaj   +1 more source

Extraction of Curcumin [PDF]

open access: yesIOSR Journal of Environmental Science, Toxicology and Food Technology, 2012
Curcumin due to its various medicinal, biological, pharmacological activities is high on demand and has high market potential, high cost. Since curcumin has variety of uses, extracting it in a less expensive method other Super Critical Fluid Extraction is the main aim or objective of this work.
openaire   +1 more source

In vitro evaluation of antioxidant and neuroprotective effects of curcumin loaded in Pluronic micelles

open access: yesBiotechnology & Biotechnological Equipment, 2016
Curcumin is a polyphenolic substance with attractive pharmacological activities (e.g. antioxidant, anti-inflammatory, anticancer). Incorporation of curcumin in polymeric micelles could overcome the problems associated with its instability and low aqueous
Cvetelina Gorinova   +6 more
doaj   +1 more source

Advanced modification of drug nanocrystals by using novel fabrication and downstream approaches for tailor-made drug delivery [PDF]

open access: yes, 2019
Drug nanosuspensions/nanocrystals have been recognized as one useful and successful approach for drug delivery. Drug nanocrystals could be further decorated to possess extended functions (such as controlled release) and designed for special in vivo ...
Haipeng, Yin   +3 more
core   +1 more source

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

open access: yesChemistry &Biodiversity, Accepted Article.
Objective: Cancer remains a global health challenge, necessitating new therapeutic options. Phytochemicals, with diverse chemical structures and biological activities, show promise as anticancer agents. This review explores key phytochemicals, their mechanisms, and their potential integration into cancer therapy.
Alaa A. A. Aljabali   +11 more
wiley   +1 more source

Evaluation of in vitro antileishmanial activity of curcumin and its derivatives "gallium curcumin, indium curcumin and diacethyle curcumin".

open access: yesEuropean review for medical and pharmacological sciences, 2014
Leishmania parasites are intracellular haemoflagellates that infect macrophages of the skin and viscera to produce diseases in their vertebrates hosts. Antileishmania therapy is based on pentavalent antimony compounds which toxicity of these agents and the persistence of side effects are severe. Curcumin was identified to be responsible for most of the
FOULADVAND, moradali   +2 more
openaire   +1 more source

Curcumin as an Alternative Epigenetic Modulator: Mechanism of Action and Potential Effects

open access: yesFrontiers in Genetics, 2019
Curcumin (a polyphenolic compound in turmeric) is famous for its potent anti-inflammatory, anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic modulator.
F. Hassan   +6 more
semanticscholar   +1 more source

Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants

open access: yesChemistry &Biodiversity, EarlyView.
The study workflow utilized validated in silico [molecular docking, fingerprinting, pharmacokinetics prediction, molecular dynamics (MD) simulation, ligand‐protein contact maps] tools to bioprospect a wide variety of metabolites surveyed from South African plants with antimicrobial activities, and target them against the key S.
Christiana Eleojo Aruwa, Saheed Sabiu
wiley   +1 more source

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