Results 181 to 190 of about 213,267 (396)

Ethnomedicinal uses, phytochemistry, pharmacological activities, and toxicology of the subfamily Gomphrenoideae (Amaranthaceae): A comprehensive review

open access: yesChemistry &Biodiversity, Accepted Article.
The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its promising ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential

open access: yesChemBioEng Reviews, EarlyView.
This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona   +2 more
wiley   +1 more source

Highly Efficient and Stable Perovskite Solar Cells via MultiFunctional Curcumin Modified Buried Interface [PDF]

open access: yesarXiv
The buried interface between the electron transport layer and the perovskite layer suffers from severe interface defects and imperfect energy level alignment. To address this issue, this study employs a multifunctional organic molecule, curcumin, to modify the interface between SnO2 and the perovskite layer.
arxiv  

Enzymatic Synthesis of Functional PEGylated Adipate Copolymers

open access: yesChemPlusChem, EarlyView.
This study explores a one‐pot, one‐step enzymatic polycondensation process to create amphiphilic PEG‐adipate variants with improved physicochemical properties that can self‐assemble into nanoparticles. By varying hydrophobic and functionalised diols, the impact on nanoparticle formation, stability, and drug encapsulation is examined.
Eleni Axioti   +12 more
wiley   +1 more source

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

open access: yesMedicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023
Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman   +6 more
wiley   +1 more source

Remote-Controlled Activation of the Release through Drug-Loaded Magnetic Electrospun Fibers [PDF]

open access: yesarXiv
The integration of magnetic nanoparticles within fibrillar structures represents an interesting avenue for the remotely controlled release of therapeutic agents. This work presents a novel drug release platform based on electrospun magnetic fibers (EMFs) combining drugs, magnetic nanoparticles (MNPs) and mesoporous silica nanoparticles (MSNs) for ...
arxiv  

Cataract‐Causing Mutant R188C of βB2 Crystallin With Low Structural Stability is Sensitive to Environmental Stresses and Prone to Aggregates Formation

open access: yesExploration, EarlyView.
This study investigated the role of the βB2‐crystallin c.562C>T (p.R188C) mutation in congenital cataract. Clinical pedigree analysis, combined with whole‐exome sequencing (WES), identified this pathogenic variant. Bioinformatic analyses predicted destabilization of the mutant protein’s tertiary structure, potentially impairing its function.
Yibo Yu   +14 more
wiley   +1 more source

BIOAVAILABILITY OF CURCUMIN AND METHODS OF ITS ENHANCING

open access: yesРазработка и регистрация лекарственных средств, 2019
Curcumin is a hydrophobic polyphenolic compound of natural origin. Curcumin has a wide range of pharmacological effects. Curcumin is inherently poorly absorbed when ingested and has low bioavailability, in part due to a low rate of absorption in the ...
N. L. Soloveva   +2 more
doaj  

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