Toxic Tau Oligomers Modulated by Novel Curcumin Derivatives [PDF]
, 2019 The pathological aggregation and accumulation of tau, a microtubule-associated protein, is a common feature amongst more than 18 different neurodegenerative diseases that are collectively known as tauopathies.
Bucchieri, Fabio +6 more
core +1 more source
A novel multifunctional biomedical material based on polyacrylonitrile:preparation and characterization [PDF]
, 2016 Wet spun microfibers have great potential in the design of multifunctional controlled release materials. Curcumin (Cur) and vitamin E acetate (Vit. E Ac) were used as a model drug system to evaluate the potential application of the drug-loaded microfiber
Bremner, David H. +6 more
core +3 more sources
Zhejiang Daxue xuebao. Lixue ban, 2014 钯(Pd)是一种性质非常特殊的稀有过渡金属，在化学以及材料科学中具有重要地位.钯催化反应的产物中常有一定浓度的残余钯污染，需要进一步纯化和检测.因此发展用于检测Pd的技术手段很有必要.零价钯可以通过对烯丙基氧化插入而切断烯丙基醚类化合物的C—O键.基于这个反应，设计合成了荧光分子二氟硼姜黄素烯丙基醚化合物，并测试了其紫外光谱和荧光光谱，研究了其对钯化合物的选择性识别作用.结果表明，该荧光分子对二价钯并无响应，只有零价钯Pd2(dba)3使该分子荧光发生猝灭.该荧光分子对于零价钯表现出很好的选择性和响应性，
XIERongjian(谢荣建) +3 more
doaj +1 more source
The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice [PDF]
, 2007 Dissemination of metastatic cells probably occurs long before diagnosis of the primary tumor. Metastasis during early phases of carcinogenesis in high risk patients is therefore a potential prevention target.
Adriana Albini +70 more
core +1 more source
Zhongguo youzhi为探究木质素复合纳米粒子在Pickering乳液中的应用，以碱木质素为原料，采用水热法制备木质素复合纳米粒子，并以其作为稳定剂制备Pickering乳液。分析了木质素复合纳米粒子及其稳定的Pickering乳液的稳定性，并将该Pickering乳液用于包封姜黄素，研究模拟胃肠道环境下姜黄素的释放性能，并采用4种动力学模型模拟姜黄素的释放行为。结果表明：水热法制备的木质素复合纳米粒子平均粒径约为150 nm，PDI为0.1，在pH 3~9范围内保持稳定的分散状态，具备一定的pH响应能力 ...
覃善嘉1，殷亚庆1，吴晶枝1，刘幽燕1,2 QIN Shanjia1，YIN Yaqing1，WU Jingzhi1，LIU Youyan1,2
doaj +1 more source
, 2014 As the beneficial effects of curcumin have often been reported to be limited to its small concentrations, we have undertaken a study to find the aggregation properties of curcumin in water by varying the number of monomers.
Bagchi, Biman +2 more
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A novel diblock copolymer of (monomethoxy poly [ethylene glycol]-oleate) with a small hydrophobic fraction to make stable micelles/polymersomes for curcumin delivery to cancer cells [PDF]
, 2014 Curcumin is a potent natural anticancer agent, but its effectiveness is limited by properties such as very low solubility, high rate of degradation, and low rate of absorption of its hydrophobic molecules in vivo.
Erfani-Moghadam, V. +5 more
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On the properties of a single OPLS-UA model curcumin molecule in water, methanol and dimethyl sulfoxide. Molecular dynamics computer simulation results [PDF]
, 2017 The properties of model solutions consisting of a solute --- single curcumin molecule in water, methanol and dimethyl sulfoxide solvents have been studied using molecular dynamics (MD) computer simulations in the isobaric-isothermal ensemble.
Ilnytskyi, J. M. +2 more
core +2 more sources
Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]
, 2016 Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V +7 more
core +5 more sources
Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]
, 2017 Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto +10 more
core +2 more sources