Results 101 to 110 of about 617,754 (317)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A Systematic Review on the Effectiveness of the Cure Violence Approach

Inquiry: The Journal of Health Care Organization, Provision, and Financing
The Cure Violence approach applies public health epidemic control strategies to reduce violence in highly impacted communities and countries. This paper conducts a systematic review to identify studies analyzing the effectiveness of the Cure Violence ...
Charles Ransford MPP, Monique Williams PhD, Gary Slutkin MD   +2 more
doaj   +1 more source

Factors Associated with Cure and Prediction of Cure of Clinical Mastitis of Dairy Cows

Dairy
To study behavioral and productive factors to detect changes that may indicate and predict clinical mastitis cure, Holstein dairy cows (n = 60), in an automatic milking system (AMS) and equipped with behavioral monitoring collar, were monitored from the ...
Larissa V. F. Cruz, Ruan R. Daros, André Ostrensky, Cristina S. Sotomaior   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Composite material process monitoring using optical fibre grating sensors [PDF]

, 2008
In this thesis a long period grating (LPG) based sensor is investigated as a possible alternative to current process monitoring sensors used in the manufacture of composites to monitor cure. An LPG is demonstrated as a means of monitoring the cure of a
Buggy, Stephen J.
core  

Urban Cross-cutting Applications Preparation (CURE Deliverable D3.1)

, 2020
This document aims to describe in more detail the CURE cross-cutting applications and to summarize the preparatory activities for the individual applications development, following the first description in Methodology Review and Selection Deliverable (D1.
Kolomaznik, Jan, Holt Andersen, Birgitte, Leutner, Benjamin, Gandini, Alessandra, Lauwaet, Dirk, Kopecky, Miroslav, Soukup, Tomas, Feigenwinter, Christian, Kjær-Hansen, Louise, Gutierrez, Laura, Feliu Torres, Efren, Lantzanakis, Giannis, Mitraka, Zina, Jupova, Katerina, Marconcini, Mattia, Hooyberghs, Hans, Chrysoulakis, Nektarios   +16 more
core   +1 more source

Surface porosity development in tool-side facesheets of honeycomb core sandwich structures during co-cure

, 2022
Co-cure of honeycomb core sandwich structures combines the consolidation of composite prepreg facesheets with bonding of facesheets to a low-density core in a single thermal cycle for efficient manufacturing.
Elana Wadhwani (12428089), Daniel Zebrine (9273651), Steven Nutt (1948354)   +2 more
core   +1 more source

Rethinking our strategies to develop disease-modifying therapies for Parkinson's: Time for combination therapies?

Journal of Parkinson’s Disease
Despite significant advances in our understanding of Parkinson's disease (PD) over the last three decades, no disease-modifying therapies (DMTs) have been identified.
Paloma Fernandez, Rachel M Hughes, Helen Matthews, Joy Duffen, Radi Haloub, Anthony H Schapira, Simon RW Stott   +6 more
doaj   +1 more source

Stage IV lung cancer: Is cure possible?

Indian Journal of Medical and Paediatric Oncology, 2013
Reporting a case, 53 years old male with stage IV Nonsamall cell lung cancer in view of cytologically proven malignant pleural effusion. Usually the management of stage IV lung cancer is with palliative intent where the patient receives palliative ...
Ravi Thippeswamy, Vanita Noronha, Vamshi Krishna, Amit Joshi, Munita Meenu Bal, Nilendu Purandare, V Rangarajan, C S Pramesh, Sabita Jiwnani, Kumar Prabhash   +9 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source