Results 121 to 130 of about 617,754 (317)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
State of the Cure: A Look at 2013's Progress Toward a Cure for Type 1 Diabetes
This report covers four main topics related to Practical Cure progress. First, it assesses the significant impact that type 1 has on many Americans. Of particular note here is donors' strong support for a Practical Cure.
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Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Trade card advertising Russian Eclectic Liniment, a remedy prepared by the Russian Sure Cure Manufacturing Co., New York, N.Y.
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Craig A, Emter, Douglas K, Bowles
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
L’Organizzazione Mondiale della Sanità e l’Associazione Europea di Cure Palliative definiscono le Cure Palliative come: “La somministrazione di cure attive e complete, nel momento in cui la malattia non risponde più al trattamento curativo.
A. Pasquarella +2 more
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PP 1.23 – 00130 Long-read sequencing assay allows accurate characterization of the HIV-1 reservoir
L. Lambrechts +7 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source

