Results 181 to 190 of about 617,754 (317)

Characterisation of immune exhaustion in natural killer cells and role in HIV infection

Journal of Virus Eradication, 2017
C. Garrido, B. Allard, N. Soriano-Sarabia, D. Margolis   +3 more
doaj   +1 more source

Joint Frailty Mixture Cure Model for Recurrent Event Data With Dependent Censoring: An MCEM Approach. [PDF]

Stat Med
Sultana N, Alam M, Hasinur Rahaman Khan M.   +2 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Cure palliative e qualità della vita nell’evoluzione della deontologia medica

, 2016
L’evoluzione della deontologia medica in Italia rivela la centralità riconosciuta ai principi etici di beneficenza, rispetto per l’autonomia, proporzionalità delle cure, nella relazione medico – paziente.
CONTI, Adelaide, DELBON, Paola, Zaninetta, Giovanni   +2 more
core  

Autologous regenerative cell therapy for female stress urinary incontinence: a systematic review and meta-analysis of clinical outcomes. [PDF]

Front Med (Lausanne)
Chen J, Zhi Y, Liu W, Fan Y, Lin Y, Zhong Q, Zhang X, Ruan X.   +7 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A CURE for synthetic regulation of gene expression: rapid screening of guide RNA efficacy as a framework for enabling undergraduate research in plant synthetic biology. [PDF]

Synth Biol (Oxf)
Bull T, Carlsen L, Hoglund N, Blarr J, Ciernia M, Daughtrey H, Gulnac K, Kathan Z, Labovitz B, Lonergan R, McDermott M, Medina A, Mikol Z, Miller Z, Prahl K, Rifai C, Schrems E, Shinkawa F, Summerfield J, Thevarajah E, Wagner S, Zimmerman T, Khakhar A.   +22 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

THE EVOLUTION OF PALLIATIVE CARE: HISTORY, STATE OF THE ART AND FUTURE PERSPECTIVES

reservedLe Cure Palliative, pur essendo state istituite alla fine del secolo scorso, affondano le loro radici nelle civiltà antiche. Sebbene il motto ippocratico "opus divinum est sedare dolorem" non sia mai stato del tutto ignorato, è solo a partire ...
VINCENTI, HELGA
core  

La formazione pre-laurea sulle cure palliative presso l'Università degli Studi di Milano

, 2014
Nell’a.a. 2014-2015 sarà avviata una sperimentazione nel Corso di Laurea in Medicina (Polo S. Paolo –Università degli Studi di Milano) che prevede l’inserimento “strutturato” dell’insegnamento della nuova disciplina Cure palliative in diversi momenti ...
A. Destrebecq, S. Scarone, F. Onida, S. Terzoni, A. Cozzolino, B. Andreoni   +5 more
core