Results 161 to 170 of about 482,314 (268)

Risk Factors and Prediction of Chronic Obstructive Pulmonary Disease After Pulmonary Tuberculosis: A Prospective Cohort Study. [PDF]

Int J Chron Obstruct Pulmon Dis
Ye X, Le S, Han S, Zhang Z, Li Q, Gao F.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The cure conundrum [PDF]

Nature Medicine, 2012
openaire   +2 more sources

Comparative effectiveness of ivermectin versus permethrin for the treatment of scabies: an updated systematic review and meta-analysis. [PDF]

BMC Infect Dis
Innocent DC, Innocent RC, Anyakorah PE, Chukwuemeka PS, Eugene C, Anuwe JC, Udoh OU, Nwachukwu BC, Obani SI, Dozie INS, Chukwuocha UM, Okwara DI, Moroh JE, George TC, Blessing AA, Efe JJ.   +15 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A bibliometric analysis of immunotherapy for chronic hepatitis B: trends and hotspots prediction. [PDF]

Front Immunol
Jin X, Tang Y, Ma Y, Li M, Gao Y.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Editorial: Biomarkers in Leishmaniasis

Frontiers in Cellular and Infection Microbiology, 2019
Eugenia Carrillo, Javier Moreno
doaj   +1 more source

Quantifying statistical cure in unresectable locally advanced esophageal squamous cell carcinoma treated with radiotherapy-based regimens: a cure model analysis with SEER validation. [PDF]

Front Oncol
Wang N, Zhang X, Zheng X, Wang X, Jiang Y, Zhang Z, Zhao Y, Xiao Y, Yang S, Zhu L, Tang X, Li B, Li Y, Bi N, Ge H.   +14 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source