Results 101 to 110 of about 62,042 (263)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Influence of Super Absorbent Polymer (SAP) on Mechanical, Durability Properties, and Internal Curing Mechanism of Cement Stabilized Macadam in Desert Environment

open access: yesAdvances in Civil Engineering
Semi-rigid base materials in desert areas are susceptible to fast evaporation of water due to high-temperature and dry environment during construction and curing, leading to insufficient cement hydration and shrinkage cracking, thus affecting the ...
Jiachen Ma   +5 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Influence of post-fire recuring regimes on the properties of self-compacting concrete with heavyweight aggregate

open access: yesScientific Reports
Fire safety is essential in construction, as accidental fires subject concrete structures to high temperatures that result in significant damage.
Taher A. Tawfik   +7 more
doaj   +1 more source

UV LED Curing for Silicone Hydrogel Contact Lenses: Breakthrough in Curing Properties and Cosmetic Characteristics

open access: yesPolymers
Ultraviolet light-emitting diode (UV LED) technology offers advantages over conventional UV mercury (UV Hg) lamps, including precise wavelength control, high energy efficiency and rapid curing. While UV LED is widely applied in sectors like dentistry, printing, and electronics, its application in contact lens manufacturing remains relatively low.
Saravanan Nanda Kumar   +5 more
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Experimental Study on Strength and Microstructure of Loess Improved by CG-2 Curing Agent and Cement

open access: yesBuildings
In order to study the improvement effect of the CG-2 curing agent and cement on loess, a series of physical and mechanical property tests and microstructure tests were carried out on loess improved with different dosages of curing agent and cement to ...
Xuening Ma   +4 more
doaj   +1 more source

EFFECT OF CURING METHOD AND CURING PERIOD ON CHARACTERISTIC OF COMPRESSIVE STRENGTH FOR Ca CONCRETE

open access: yesCement Science and Concrete Technology, 2009
SHIMABUKURO, Atsushi   +1 more
openaire   +2 more sources

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