Results 91 to 100 of about 9,707 (256)
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Electrical Tree Characteristics of Bisphenol A Epoxy Resin/Maleopimaric Anhydride Curing System
, 2022 Epoxy resin insulation materials are mainly derived from petrochemical materials which have the disadvantages of resource consumption and environmental pollution.
Xuan Wu +13 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
What are Future Curing Lights Technology Trends?
, 2010 Over the recent years, dental curing lights as well as light-cured materials have been undergoing rapid development, which makes choosing a curing light guaranteeing the optimal polymerization degree difficult.
D. Houšová +3 more
core
Experimental Study of Stress-Strain Characteristics of the Fly Ash Blended with Curing Agent
, 2010 The stress-strain characteristics of the fly ash blended with curing agent was studied using uniaxial and triaxial compression tests. Curing agent JNS-2 was used as the stabilizing agents in sample preparation. Four curing agent JNS-2 contents of 3%, 6%,
Lan Zong, Xiang Dong, Zheng Shen
core +1 more source
STRENGTH CHARACTERISTICS OF SELF-CURING CONCRETE
International Journal of Research in Engineering and Technology, 2012 Today concrete is most widely used construction material due to its good compressive strength and durability. Depending upon the nature of work the cement, fine aggregate, coarse aggregate and water are mixed in specific proportions to produce plain concrete.
openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Cure Characteristics of Foaming EVA Compounds: Influence of EVA Types and Cure Systems
Elastomers and Composites, 2016 Influence of poly(ethylene-co-vinyl acetate) (EVA) types and cure systems on cure characteristics of foaming EVA compounds were investigated. Three kind EVAs with different VA contents were employed. Influence of triallyl cyanurate (TAC) and dicumylperoxide (DCP) content on the cure characteristics were examined.
Sung-Seen Choi +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source