Results 51 to 60 of about 10,455 (248)

Selective inhibition of the amyloid matrix of Escherichia coli biofilms by a bifunctional microbial metabolite

npj Biofilms and Microbiomes, 2023
The propensity of bacteria to grow collectively in communities known as biofilms and their ability to overcome clinical treatments in this condition has become a major medical problem, emphasizing the need for anti-biofilm strategies.
Estefanía Cordisco, María Inés Zanor, Diego Martín Moreno, Diego Omar Serra   +3 more
doaj   +1 more source

Uncovering a previously unknown function of polyphosphate in polyadenylated RNA‐induced amyloidogenesis of Hfq

The FEBS Journal, EarlyView.
Polyphosphate interaction with Hfq and RNA drives phase separation and amyloid self‐assembly, uncovering a previously unrecognized role for polyP in bacterial stress responses. Our findings reveal new insights into the molecular mechanisms of RNA‐mediated phase separation, highlighting the role of polyP as a key modulator of this process. Polyphosphate
Kevin Mosca, Florian Turbant, Sambhasan Banerjee, Frank Wien, Richard R. Sinden, Véronique Arluison   +5 more
wiley   +1 more source

Microanatomy at Cellular Resolution and Spatial Order of Physiological Differentiation in a Bacterial Biofilm

mBio, 2013
Bacterial biofilms are highly structured multicellular communities whose formation involves flagella and an extracellular matrix of adhesins, amyloid fibers, and exopolysaccharides.
Diego O. Serra, Anja M. Richter, Gisela Klauck, Franziska Mika, Regine Hengge   +4 more
doaj   +1 more source

bolA gene involved in curli amyloids and fimbriae production in E. coli: exploring pathways to inhibit biofilm and amyloid formation

Journal of Biological Research - Thessaloniki, 2020
Background Biofilm formation is a complex phenomenon of bacterial cells, involved in several human infections. Its formation is regulated and controlled by several protein factors.
Mohd W. Azam, Azna Zuberi, Asad U. Khan
doaj   +1 more source

Gene clusters reflecting macrodomain structure respond to nucleoid perturbations

, 2010
Focusing on the DNA-bridging nucleoid proteins Fis and H-NS, and integrating several independent experimental and bioinformatic data sources, we investigate the links between chromosomal spatial organization and global transcriptional regulation.
Alberts, Ashburner, Babu, Ball, Beloin, Berger, Bertin, Bianca Sclavi, Blot, Boccard, Bradley, Bruno Bassetti, Cabrera, Cabrera, Cases, Chilcott, Cho, Cho, Cook, Cunha, Cunha, Dame, Darling, Dillon, Dorman, Duan, Eisen, Esnault, Espéli, Espéli, Fang, Gama-Castro, Grainger, Hengen, Hengge, Janga, Jeong, Jin, Junier, Kahramanoglou, Kalir, Kalir, Kelly, Keseler, Ko, Korea, Krin, Képès, Képès, Lang, Liu, Luijsterburg, Marco Cosentino Lagomarsino, Marr, Mathelier, Mercier, Moulin, Muskhelishvili, Nielsen, Oberto, Ogasawara, Oshima, Pesavento, Peter, Postow, Prigent-Combaret, Prüss, Reyes-Lamothe, Rocha, Saldana, Serres, Smith, Sonnenschein, Soutourina, Soutourina, Soutourina, Travers, Valens, Vittore F. Scolari, Vora, Wade, Wang, Wang, Wang, Warren, Weber, Wiggins, Wright, Zechiedrich, Zimmerman   +89 more
core   +2 more sources

Whole‐Genome Sequence Profiling of Listeria innocua From Different Sources: Implications for Public Health

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
The studied strains, LIN_NWU_CNKT and LIN5_NWU_CNKT, exhibit invasiveness, pathogenicity, and MDR profiles. The isolation of these strains from food products and water underscores their significant public health implications, particularly in the context of the “One Health” concept.
Christ‐Donald Kaptchouang Tchatchouang, Daniel Jesuwenu Ajose, Giulia Amagliani, Collins Njie Ateba   +3 more
wiley   +1 more source

Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37.

PLoS Pathogens, 2010
Bacterial growth in multicellular communities, or biofilms, offers many potential advantages over single-cell growth, including resistance to antimicrobial factors.
Ylva Kai-Larsen, Petra Lüthje, Milan Chromek, Verena Peters, Xiaoda Wang, Asa Holm, Lavinia Kádas, Kjell-Olof Hedlund, Jan Johansson, Matthew R Chapman, Stefan H Jacobson, Ute Römling, Birgitta Agerberth, Annelie Brauner   +13 more
doaj   +1 more source

Purification of the Bacterial Amyloid “Curli” from Salmonella enterica Serovar Typhimurium and Detection of Curli from Infected Host Tissues

Bio-Protocol, 2022
Microbiologists are learning to appreciate the importance of “functional amyloids” that are produced by numerous bacterial species and have impacts beyond the microbial world. These structures are used by bacteria to link together, presumably to increase
Murugesan Sivaranjani, Elizabeth Hansen, Sumudu Perera, Pamela Flores, Cagla Tukel, Aaron White   +5 more
doaj   +1 more source

Transcriptional profile of Salmonella enterica subsp. enterica serovar Weltevreden during alfalfa sprout colonization [PDF]

, 2013
Sprouted seeds represent a great risk for infection by human enteric pathogens because of favourable growth conditions for pathogens during their germination.
Brankatschk, Kerstin, Duffy, Brion, Kamber, Tim, Pothier, Joël F., Smits, Theo H.M.   +4 more
core   +1 more source

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source