Results 71 to 80 of about 85,328 (319)
Central bank digital currencies: A critical review
Lambis Dionysopoulos +2 more
openalex +1 more source
It would be good if the mass of data that the healthcare purchasers are creating could be used for more than just billing purposes. In practice, healthcare services are legitimized through diagnoses. Longer consultations that exceed the restrictions imposed by flat rates can be bailed only by using “psycho-codes”. For this reason, “psycho-diagnoses”
openaire +2 more sources
The role of fibroblast growth factors in cell and cancer metabolism
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
While Aristotle’s and St. Thomas’s teachings about economics are often ridiculed today, this article argues that actually what they had to say about this issue, especially about the nature of sound currency, backed up by force of law, is quite profound ...
Peter A. Redpath
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
De-Dollarisation in International Payments: Trend or Fiction
The present research paper is focused the widely debated topic related to de-dollarization. It examines the trend of de-dollarization to check if the statements that the dollar is losing its weight and is about to lose its leading position in ...
Todorova Vesela +2 more
doaj +1 more source
CHINESE YUAN EXCHANGE RATE AGAINST THE INDONESIAN RUPIAH PREDICTION USING SUPPORT VECTOR REGRESSION
This study aims to forecast the exchange rate between the Chinese Yuan (CNY) and the Indonesian Rupiah (IDR) using Support Vector Regression (SVR), a machine-learning technique that can handle nonlinear and complex data.
Steven Soewignjo +5 more
doaj +1 more source

