Results 41 to 50 of about 361,415 (340)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Video signal processing system uses gated current mode switches to perform high speed multiplication and digital-to-analog conversion [PDF]

, 1966
Video signal processor uses special-purpose integrated circuits with nonsaturating current mode switching to accept texture and color information from a digital computer in a visual spaceflight simulator and to combine these, for display on color CRT ...
Gilliland, M. G., Rougelot, R. S., Schumaker, R. A.   +2 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Precision Analog Rectifiers With Current Input-Current Output Topologies: A Comprehensive Study

Electrica
: Precision rectifiers play a crucial role in modern electronics, providing accurate signal processing and energy conversion for a wide range of applications.
Muhammed Emin Başak
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Operational Current Amplifier-Based Quadrature Oscillators Family

IEEE Access
This paper investigates the application of the operational current amplifier (OCA) in the design of quadrature sinusoidal oscillators. There are numerous quadrature sinusoidal oscillators based on the three fundamental amplifiers namely the operational ...
Hussain A. Alzaher, Ibrahim M. Alkhalifa
doaj   +1 more source

A Single-Ended and Fully-Differential Universal Current-Mode Frequency Filter with MO-CF and DACA Elements

Advances in Electrical and Computer Engineering, 2016
The paper presents proposal of the 2nd-order universal frequency filter. The presented filter operates in the current-mode and it is designed in the single-ended and fully-differential form. Signal-flow graphs (SFG) method has been used in the proposal.
LANGHAMMER, L., JERABEK, J., POLAK, J., PANEK, D.   +3 more
doaj   +1 more source

Very wide range tunable CMOS/bipolar current mirrors with voltage clamped input [PDF]

, 1999
In low power current mode signal processing circuits it is often necessary to use current mirrors to replicate and amplify/attenuate current signals and clamp the voltage of nodes with high parasitic capacitances so that the smallest currents do not ...
Andreou, Andreas G., Linares Barranco, Bernabé, Serrano Gotarredona, María Teresa   +2 more
core   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

ATPG for Delay Defects in Current Mode Threshold Logic Circuits [PDF]

, 2016
An automatic test pattern generation approach todetect delay defects in a circuit consisting of current modethreshold logic gates is introduced. Each generated patternshould excite the maximum propagation delay at the fault site.Manufactured weights may ...
Haniotakis, Themistoklis, Palaniswamy, Ashok Kumar, Tragoudas, Spyros   +2 more
core   +2 more sources