Results 21 to 30 of about 9,901,771 (241)

Current Mode Biquad Filter with Minimum Component Count

Active and Passive Electronic Components, 2011
The paper presents a new current mode biquadratic filter with one input and three outputs using differential voltage current conveyor (DVCC) and four passive components.
Bhartendu Chaturvedi, Sudhanshu Maheshwari   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Active Power Filter With Automatic Control Circuit For Neutral Current Harmonic Minimization Technique [QC446.3.H37 I98 2007 f rb]. [PDF]

, 2007
Disertasi ini bertujuan untuk membangun penuras kuasa aktif yang cekap dan boleh dipercayai bagi meminimumkan lebihan harmonik arus neutral dan juga masalah harmonik di dalam talian neutral untuk sistem tiga fasa empat dawai. The aim of this thesis
A Bakar, Mohd Izhar
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

'Switched-Current Wave Group Delay Equalizers'

, 2004
To improve the elliptic filters step response, group delay equalizers are often cascaded with the filters. This paper describes the design of switched-current (SI) group delay equalizer using wave synthesis technique.
Xie, Yan, Al-Hashimi, Bashir
core   +1 more source

Current-Mode Shadow Filter with Single-Input Multiple-Output Using Current-Controlled Current Conveyors with Controlled Current Gain

Sensors
In this paper, a novel current-mode shadow filter employing current-controlled current conveyors (CCCIIs) with controlled current gains is presented. The CCCII-based current-mode shadow filters are resistorless and can offer a number of advantages such ...
Montree Kumngern, Fabian Khateb, Tomasz Kulej, Martin Kyselak, Somkiat Lerkvaranyu, Boonying Knobnob   +5 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source