Results 41 to 50 of about 206,461 (264)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

A 3rd-order current-mode filter in 0.12 μm CMOS [PDF]

open access: yesAdvances in Radio Science, 2008
For software radio applications in system-on-chips, a 3rd-order current-mode Butterworth filter in 120 nm CMOS is realized. This filter is used for reconstruction purposes between a current-steering DAC and a current-mode mixer.
R. Kolm, H. Zimmermann
doaj  

Reconfigurable Mixed Mode Universal Filter

open access: yesActive and Passive Electronic Components, 2014
This paper presents a novel mixed mode universal filter configuration capable of working in voltage and transimpedance mode. The proposed single filter configuration can be reconfigured digitally to realize all the five second order filter functions ...
Neelofer Afzal, Devesh Singh
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Low-Voltage Current-Mode Analog Filter Using Current Differencing Transconductance Amplifier

open access: yesIEEE Access
This paper presents a new low-voltage, low-power current-mode active filter with three inputs and seven outputs. The design is implemented using three current differencing transconductance amplifiers (CDTAs) and two grounded capacitors.
Montree Kumngern   +2 more
doaj   +1 more source

New Universal Current-Mode Filter Using Non-Inverting Second-Generation Current-Conveyors

open access: yesActive and Passive Electronic Components, 1995
A new universal active current-mode filter with single input and five outputs is presented. The proposed filter avoids the use of feedback in any part of the circuit and uses only one type of second-generation current-conveyors, grounded resistors, and ...
Muhammad Taher Abuelma'atti   +1 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

New Universal One-Input Five-Output Current-Mode Filter Using Current-Conveyors

open access: yesActive and Passive Electronic Components, 1995
A new universal active current-mode filter with single input and five outputs is presented. The proposed filter avoids the use of feedback in any part of the circuit and uses only grounded resistors and grounded capacitors.
Muhammad Taher Abuelma'atti   +1 more
doaj   +1 more source

New Multifunctional Frequency Filter Working in Current-mode [PDF]

open access: yes, 2007
Increasing demands on circuits with low supply voltage and low power consumption lead to the realization of analogue circuits working in the current-mode. In this paper a new topology is presented of multifunctional frequency filter SIMO (Single Input Multiple Output) working the in currentmode.
Jaroslav Koton, Kamil Vrba
openaire   +1 more source

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