Results 51 to 60 of about 10,032,446 (297)
Dual-Mode Multifunctional Reconnection-Less Reconfigurable Filter
Elektronika ir Elektrotechnika, 2020 A novel solution of a reconnection-less reconfigurable filter is being presented. The filter works in the current mode, voltage mode, and mixed mode (voltage tocurrent) offering sixteen transfer functions in total.
Lukas Langhammer +3 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Single CDTA-Based Current Mode All-Pass Filter and Its Applications
Journal of Electrical and Computer Engineering, 2011 This paper presents a single current difference transconductance amplifier (CDTA) based all-pass current mode filter. The proposed configuration makes use of a grounded capacitor which makes it suitable for IC implementation.
Neeta Pandey, Sajal K. Paul
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Applied SciencesThis paper presents a mixed-mode universal filter using differential difference current conveyor transconductance amplifiers (DDCCTA). Despite using a minimum number of MOS differential pairs, the proposed DDCCTA is a multiple-input, multiple-output ...
Montree Kumngern +2 more
doaj +1 more source
Applied Sciences, 2017 A new electronically tunable mixed-mode biquadratic filter with three current controlled current conveyor transconductance amplifiers (CCCCTAs) and two grounded capacitors is proposed. With current input, the filter can realise lowpass (LP), bandpass (BP)
Hua-Pin Chen, Wan-Shing Yang
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Synthesis of switched-current Ladder Derived Group delay Equalizers
, 2002 This paper describes the design of switched-current group delay equalizers. The design process is based on the pole-zero mirroring technique; with equalizer z-transfer functions generated using an optimization algorithm.
Al Hashimi, Bashir, Xie, Yan
core +1 more source