Results 61 to 70 of about 10,032,446 (297)

A Current Mode Design of Fractional Order Universal Filter

open access: yesAdvances in Electrical and Computer Engineering, 2019
In this paper, low-voltage active elements based a general filter topology, which provides fractional order low-pass, high-pass, band-pass and band-reject filter responses at the same circuit, is introduced.
SACU, I. E., ALCI, M.
doaj   +1 more source

Current mode biquadratic filter realizations employing operationalamplifiers [PDF]

open access: yes, 1994
New circuit configurations for realizing current mode biquadratic filter sections using operational amplifiers are presented. Each circuit uses a single operational amplifier and seven passive elements at most.
Abuelma’atti, M.T.
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

A 3rd-order current-mode filter in 0.12 μm CMOS [PDF]

open access: yesAdvances in Radio Science, 2008
For software radio applications in system-on-chips, a 3rd-order current-mode Butterworth filter in 120 nm CMOS is realized. This filter is used for reconstruction purposes between a current-steering DAC and a current-mode mixer.
R. Kolm, H. Zimmermann
doaj  

Reconfigurable Mixed Mode Universal Filter

open access: yesActive and Passive Electronic Components, 2014
This paper presents a novel mixed mode universal filter configuration capable of working in voltage and transimpedance mode. The proposed single filter configuration can be reconfigured digitally to realize all the five second order filter functions ...
Neelofer Afzal, Devesh Singh
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Low-Voltage Current-Mode Analog Filter Using Current Differencing Transconductance Amplifier

open access: yesIEEE Access
This paper presents a new low-voltage, low-power current-mode active filter with three inputs and seven outputs. The design is implemented using three current differencing transconductance amplifiers (CDTAs) and two grounded capacitors.
Montree Kumngern   +2 more
doaj   +1 more source

Operational Transresistance Amplifier Based Current-Mode All-pass Filter Topologies

open access: yes, 2021
Three new current-mode filter topologies are proposed. The presented topologies use single operational transresistance amplifier (OTRA). To demonstrate the performance of the proposed filter a new current-mode quadrature oscillator is given as an ...
Kacar, Firat
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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