Results 121 to 130 of about 10,981,473 (283)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Current Concepts in Myopia Control
Collegium antropologicum, 2013 Current animal and human models of myopia progression show that beside genetics, there are several environmental factors that contribute to the axial elongation process, the underlying cause for progressive myopia. During last years, extensive research in this field revealed some apparently independent mechanisms, which play an important role in ...
openaire +3 more sources
Translinear current-controlled current amplifier
Electronics Letters, 1988 A bipolar current amplifier built from translinear elements (i.e. mixed loop and current mirrors) is described. Its current gain is determined by the ratio of two direct currents. Experimental results are given and discussed.
openaire +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
A comprehensive insight into current control of COVID-19: Immunogenicity, vaccination, and treatment. [PDF]
Biomed Pharmacother, 2022 Mohamed Y +5 more
europepmc +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
A sophisticated design of copper core to converge rotating eddy current control for detecting cracks in conductive materials. [PDF]
Sci Rep, 2023 Trung LQ, Kasai N, Sekino K, Miyazaki S.
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Exploring Damping Effect of Inner Control Loops for Grid-Forming VSCs
IEEE Open Journal of Power ElectronicsThis paper presents an analytical framework to evaluate the damping contributed by inner control loops in grid-forming voltage-source converters. First, an impedance model is developed to characterize the dynamics of three types of inner loops, with the ...
Liang Zhao, Xiongfei Wang, Zheming Jin
doaj +1 more source