Results 141 to 150 of about 4,453,263 (297)

Buck Converter Modelling for Supercapacitors Fast Charging in CCM

open access: yesPower Electronics and Drives
Supercapacitors (SCs) can handle thousands of charge/discharge cycles with high peak currents, largely due to their low equivalent series resistance (ESR).
Quintáns Graña Camilo   +2 more
doaj   +1 more source

Prevalence and aetiologies of anaemia among first trimester pregnant women in Sri Lanka; the need for revisiting the current control strategies. [PDF]

open access: yesBMC Pregnancy Childbirth, 2022
Amarasinghe GS   +5 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Low-complexity constrained control of the opposed current converter using quadratic control contractive sets

open access: yes, 2014
The opposed current converter (OCC) is a high-precision power amplifier that does not require blanking time in between switching and hence has high output quality.
Schellekens, J.M.; id_orcid   +8 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Improved Design of Excitation Voltage Adjustment System for Power Support Van Based on Saber Simulation

open access: yesKongzhi Yu Xinxi Jishu, 2011
Aiming to the problems existing in the excitation voltage adjustment system of aircraft power support van such as slow dynamic response speed and the poor output voltage stability, it proposes a scheme of introducing DC supply control to the excitation ...
王余奎, 赵徐成, 常军, 王云皓
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Digital current mode control for multiple input converters

open access: yes, 2012
textIn this thesis, the possibility of applying digital current mode control on multiple-input (MI) converters is studied. As for MI topologies having a central energy transfer inductor, the predictive constant on-time current-mode control can greatly ...
Ding, Guanyu, 1987-
core  

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