Results 91 to 100 of about 10,375,169 (303)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Effect of Transformer Magnetizing Inductance on a Forward Converter with Current Mode Control
[[abstract]]The small-signal model for a forward converter with current-mode control is derived which includes the magnetizing inductance of the main power transformer.
Chen, S. Y. ; Huang, K. ; Chen, Jin-Jia
core
Drive current of accumulation-mode p-channel SOI-based wrap-gated Fin-FETs
Comparisons are performed to study the drive current of accumulation-mode(AM) p-channel wrap-gated Fin-FETs. The drive current of the AM p-channel FET is15%-26% larger than that of the inversion-mode(IM) p-channel FET with the same wrap-gated fin channel,
Zhang, Yanbo +12 more
core +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
A High-Precision Voltage-Quantization-Based Current-Mode Computing-in-Memory SRAM. [PDF]
Zhao R, Gong Z, Liu Y, Chen J.
europepmc +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Most of the floating tunnel and supporting tendon or cable of submerged floating tunnel (SFT) are essentially cylindrical body. Multi-mode vortex- induced vibration (VIV) of these flexible bodies frequently happens in non-uniform flow due to structural ...
陈伟民 +6 more
core +1 more source
A Modified Current-Mode VCSEL Driver for Short-Range LiDAR Sensor Applications in 180 nm CMOS
This paper presents a modified current-mode vertical-cavity surface-emitting laser (VCSEL) driver as a transmitter for short-range light detection and ranging (LiDAR) sensors, where a stable bias generator is suggested with a regulated cascode current ...
Juntong Li +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Current-Mode VLSI Analog Filters
Current-mode design is of great interest to high-tech analog designers today, who are principally concerned with designing whole systems on a chip. This work focuses on the theory and methods of many important current-mode circuit design techniques ...
P. V. Ananda Mohan, Mohan, P. V. Ananda
core +1 more source

