Results 81 to 90 of about 1,015,715 (265)

Single-Input Four-Output Current Mode Filter Using Operational Floating Current Conveyor

open access: yesActive and Passive Electronic Components, 2013
This paper presents operational floating current conveyor (OFCC) based single input four output current mode filter. It employs only three OFCCs and two grounded capacitors and resistors each.
Neeta Pandey, Deva Nand, Zubair Khan
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

CMOS Current-Mode Companding Divider

open access: yesIEICE Transactions on Electronics, 2009
A CMOS current-mode companding divider is presented. Currents of both dividend and divisor are compressed into log-domain. Then the logarithm current of divisor is subtracted from the logarithm current of dividend. After expanding the subtraction result, the division function could be achieved.
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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