Results 81 to 90 of about 10,375,169 (303)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A Capacitor-Grounded Current-Tunable Current Mode All-Pass Network [PDF]

open access: yes, 2020
A first-order current-mode all-pass section (CM-APS) using two current-controlled conveyors ...
Montree Kumngern   +3 more
core  

Voltage-Mode and Current-Mode Resistorless Third-Order Quadrature Oscillator

open access: yesApplied Sciences, 2017
This paper presents the realization of a resistorless third-order quadrature oscillator using two multiple-output current controlled current conveyor transconductance amplifiers (MO-CCCCTAs) and three grounded capacitors.
Hua-Pin Chen   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Programmable Current-Mode Universal Active Filters Employing Current Conveyors

open access: yesActive and Passive Electronic Components, 1998
Novel current-mode active filter circuits using current-conveyors are presented. The proposed circuits can realize all standard second-order filter functions.
Muhammad Taher Abuelma'atti
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Current-mode flash analog-to-digital converter [PDF]

open access: yes
This thesis describes the development of a flash analog-to-digital converter based on current-mode technique. The advantages of current -mode technique are higher speed, smaller chip area, and simple division of reference current based on current mirror.
Maleki, Mohammad
core   +4 more sources

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