Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
An Inductive Voltage/Current-Mode Integrated Power Management with Seamless Mode Transition and Energy Recycling. [PDF]
Gougheri HS, Kiani M.
europepmc +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
A 2.4 GHz Wide-Range CMOS Current-Mode Class-D PA with HD2 Suppression for Internet of Things Applications. [PDF]
Kim NS.
europepmc +1 more source
16-Channel biphasic current-mode programmable charge balanced neural stimulation. [PDF]
Li X, Zhong S, Morizio J.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Current-Mode Shadow Filter with Single-Input Multiple-Output Using Current-Controlled Current Conveyors with Controlled Current Gain. [PDF]
Kumngern M +5 more
europepmc +1 more source
A Dual-Output Reconfigurable Shared-Inductor Boost-Converter/Current-Mode Inductive Power Management ASIC With 750% Extended Output-Power Range, Adaptive Switching Control, and Voltage-Power Regulation. [PDF]
Gougheri HS, Graybill P, Kiani M.
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Toward High Throughput Core-CBCM CMOS Capacitive Sensors for Life Science Applications: A Novel Current-Mode for High Dynamic Range Circuitry. [PDF]
Forouhi S, Dehghani R, Ghafar-Zadeh E.
europepmc +1 more source

