Results 151 to 160 of about 10,252,281 (255)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
A Peak Current Mode Boost DC-DC Converter with Hybrid Spread Spectrum. [PDF]
Micromachines (Basel)Zhong X, Yu J, Shen Y, Li J.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Design of low power and high speed approximate multipliers utilizing current mode 4 to 2 compressors based on CNTFET technology. [PDF]
Sci RepForoutan P, Navi K.
europepmc +1 more source
Synthesis of switched-current Ladder Derived Group delay Equalizers
, 2002 This paper describes the design of switched-current group delay equalizers. The design process is based on the pole-zero mirroring technique; with equalizer z-transfer functions generated using an optimization algorithm.
Al Hashimi, Bashir, Xie, Yan
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Design of a Current-Mode OTA-Based Memristor Emulator for Neuromorphic Medical Application. [PDF]
Micromachines (Basel)Neifar A +3 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Effortless Totem-Pole Converter Control Using a Power Factor Correction Peak Current-Mode Controller. [PDF]
Sensors (Basel)Alsalemi A, Massoud A.
europepmc +1 more source