Results 51 to 60 of about 124,007 (302)

Acoustic detection in superconducting magnets for performance characterization and diagnostics

open access: yes, 2014
Quench diagnostics in superconducting accelerator magnets is essential for understanding performance limitations and improving magnet design. Applicability of the conventional quench diagnostics methods such as voltage taps or quench antennas is limited ...
Marchevsky, M.   +3 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Nonequilibrium quantum dynamics of partial symmetry breaking for ultracold bosons in an optical lattice ring trap [PDF]

open access: yes, 2019
A vortex in a Bose-Einstein condensate on a ring undergoes quantum dynamics in response to a quantum quench in terms of partial symmetry breaking from a uniform lattice to a biperiodic one.
Carr, Lincoln D.   +5 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Runaway electron beam formation, vertical motion, termination and wall loads in EU-DEMO

open access: yesNuclear Fusion
Runaway electron (RE) loads onto material structures are a major concern for future large tokamaks due to the efficient avalanching at high plasma currents.
F. Vannini   +11 more
doaj   +1 more source

Parametric study of Alfvénic instabilities driven by runaway electrons during the current quench in DIII-D

open access: yesNuclear Fusion, 2023
To avoid or mitigate runaway electron (RE) beams in ITER, RE-driven instabilities are actively studied as a complimentary technique to massive material injection.
A. Lvovskiy   +10 more
doaj   +1 more source

Improvement of DC Fault Current Limiting and Interrupting Operation of Hybrid DC Circuit Breaker Using Double Quench

open access: yesEnergies, 2021
In this paper, direct current (DC) fault current limiting and interrupting operation of hybrid DC circuit breaker (DCCB) using double quench, which consists of DCCB, a series resonance circuit, power electronic switch, surge arrestor, two separated ...
Sang-Jae Choi   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Quenching technology: a selected overview of the current state-of-the-art [PDF]

open access: yesMaterials Research, 2005
Many papers have been published on a wide range of aspects of the fundamental physics and chemistry of quenching such as: additive technology, surface rewetting, hardness distribution prediction, role of heat transfer and residual stresses, etc.1,2.
Canale, Lauralice de Campos Franceschini   +1 more
openaire   +4 more sources

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