Results 101 to 110 of about 8,721,544 (291)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

FBG-based fibre-optic current sensors for power systems protection : laboratory evaluation [PDF]

open access: yes, 2009
Conventional differential current unit protection schemes rely on a pair of electronic protection relays that measure current phasors separately at the boundaries of the protected zone.
Niewczas, Pawel   +3 more
core   +2 more sources

Improved Current Sensor for Water Diffusion Testing of Composite Insulators

open access: yesSensors, 2019
An improved current sensor aimed at measuring currents of different parts in composite insulator samples was proposed. Conventional current sensors used in water diffusion tests aim to examine the performance of composite insulators, however, it is ...
Zhonghao Zhang   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Secure Clustering Protocols in Wireless Sensor Networks [PDF]

open access: yes, 2016
Wireless sensor networks (WSNs) are poised of huge number of low-cost and tiny devices i.e. senor nodes which communicate over wireless media. Various WSN based projects produced fruitful and interesting results that greatly improves our life.
Sharma, S C, SINGH, SANTAR PAL
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Performance Comparison of Heterogeneous EESAA in Two and Three Dimensional Wireless Sensor Networks [PDF]

open access: yes, 2016
Wireless Sensor Network is the network of limited power, computational and storage sensing devices called sensors. These sensors sense and send out data to other sensors present in the network. A considerable amount of energy is dissipated in these tasks.
somani, anisha   +1 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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