Results 101 to 110 of about 4,494,023 (283)

Metabolomics of cereals under biotic stress: current knowledge and techniques

open access: yesFrontiers in Plant Science, 2013
Prone to attacks by pathogens and pests, plants employ intricate chemical defense mechanisms consisting of metabolic adaptations. However, many plant attackers are manipulating the host metabolism to counteract defense responses and to induce favorable ...
Dirk eBalmer   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Current Trends and Research Challenges Regarding “Preparation for Oxidative Stress”

open access: yesFrontiers in Physiology, 2017
Survival under stress, such as exposure to hypoxia, anoxia, freezing, dehydration, air exposure of water breathing organisms, and estivation, is commonly associated to enhanced endogenous antioxidants, a phenomenon coined “preparation for oxidative ...
Daniel C. Moreira   +6 more
doaj   +1 more source

Characteristics of EMI generated by negative metal-positive dielectric voltage stresses due to spacecraft charging [PDF]

open access: yes, 1985
Charging of spacecraft surfaces by the environmental plasma can result in differential potentials between metallic structure and adjacent dielectric surfaces in which the relative polarity of the voltage stress is either negative dielectric/positive ...
Chaky, R. C., Inouye, G. T.
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Stress Biomarkers in Pigs: Current Insights and Clinical Application

open access: yesVeterinary Sciences
Our study aimed to contribute to the understanding of the stress process in pigs to better assess and control their stress levels. Nowadays, pigs in intensive farming are exposed to several stress factors, such as weaning, transportation, diseases and ...
Vasileios G. Papatsiros   +2 more
doaj   +1 more source

Current perspectives in proteomic analysis of abiotic stress in Grapevines

open access: yesFrontiers in Plant Science, 2014
Grapes are an important crop plant which forms the basis of a globally important industry. Grape and wine production is particularly vulnerable to environmental and climatic fluctuations, which makes it essential for us to develop a greater understanding
Iniga Seraphina George, Paul A Haynes
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy