Results 111 to 120 of about 7,340,685 (300)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Dynamic Differential Protection of Transformer Considering CT Saturation Based on Waveform Distortion Estimation

open access: yesIEEE Access
The protection relay performs a significant role in maintaining the power system’s reliability and stability. However, Current Transformer (CT) saturation affects the overcurrent, differential and distance protection under various conditions ...
Nilesh Chothani, Swapnil Kumar
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Analysis of relay protection action of grounding fault of no-load charging of a 330 kV transformer

open access: yesGong-kuang zidonghua, 2013
In view of problem that a 330 kV start-up standby transformer took place relay protection action in no-load charging, the paper indicated that the action was caused by grounding fault of A-phase current transformer through analyzing charging current ...
LYU Bin   +3 more
doaj  

Detection failure elements in digital relay protection using the example of differential logic protection and the possibility of adaptive protection

open access: yesИзвестия высших учебных заведений: Проблемы энергетики
Relevance. The efficiency and reliability of the relay protection system is influenced by many factors, such as: failure of the power switch, malfunction of the relay protection device components, errors in the operation of the current measurement, etc ...
M. V. Sharygin   +2 more
doaj   +1 more source

Máquina assíncrona trifásica de rotor bobinado duplamente alimentada por meio de transformador rotativo [PDF]

open access: yes, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2011A máquina assíncrona trifásica é um equipamento extremamente difundido no universo das máquinas ...
Ruviaro, Maurício
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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